| Saturday 3rd September 1988 | F.A. Challenge Cup Preliminary Round | ||
|---|---|---|---|
| Arnold (Merged with Arnold Kingswell) | 1-0 | Bootle | |
| Ashington | 2-4 | Rossendale United | |
| Clitheroe | 2-2 | Lancaster City | |
| Formby | 0-7 | Congleton Town | |
| Glossop | 0-0 | Prescot Cables | |
| Leyland Motors | 0-1 | Bridlington Trinity | |
| Norton & Stockton Ancients | 1-0 | Darwen | |
| St Helens Town | 0-1 | Ashton United | |
| Warrington Town | 3-2 | Curzon Ashton | |
| Wren Rovers | 0-3 | Whitley Bay | |
| Tuesday 6th September 1988 | F.A. Challenge Cup Preliminary Round Replay | ||
|---|---|---|---|
| Lancaster City | 1-0 | Clitheroe | |
| Prescot Cables | 1-0 | Glossop | |
| Saturday 10th September 1988 | F.A. Carlsberg Vase Extra Preliminary Round | ||
|---|---|---|---|
| Atherton Collieries | 1-3 | St Dominics | |
| Flixton | 1-2 | Daisy Hill | |
| General Chemicals | 5-2 | Ellesmere Port & Neston | |
| Linotype | 0-1 | Maine Road | |
| Meir K A | 2-2 | Oldham Town | |
| Nelson | 1-2 | Eppleton Colliery Welfare | |
| Poulton Victoria | 1-1 | Cheadle Town | |
| Salford | 3-1 | Warrington Rylands 1906 | |
| South Shields | 1-0 | Blackpool Mechanics | |
| Tuesday 13th September 1988 | F.A. Carlsberg Vase Extra Preliminary Round Replay | ||
|---|---|---|---|
| Cheadle Town | 1-2 | Poulton Victoria | |
| Oldham Town | 1-4 | Meir K A | |
| Saturday 17th September 1988 | F.A. Challenge Cup 1st Qualifying Round | ||
|---|---|---|---|
| Bilston Town | 0-0 | Warrington Town | |
| Blyth Spartans | 1-0 | Rossendale United | |
| Burscough | 0-1 | Emley (original) | |
| Colwyn Bay | 0-0 | Ashton United | |
| Eastwood Hanley | 2-0 | Prescot Cables | |
| Morecambe | 3-3 | Skelmersdale United | |
| Stalybridge Celtic | 1-4 | Chadderton | |
| Tuesday 20th September 1988 | F.A. Challenge Cup 1st Qualifying Round Replay | ||
|---|---|---|---|
| Ashton United | 2-1 | Colwyn Bay | |
| Skelmersdale United | 1-2 | Morecambe | |
| Warrington Town | 3-2 | Bilston Town | |
| Saturday 24th September 1988 | F.A. Trophy 1st Qualifying Round | ||
|---|---|---|---|
| Sutton Coldfield Town | 2-3 | Colwyn Bay | |
| Saturday 1st October 1988 | F.A. Challenge Cup 2nd Qualifying Round | ||
|---|---|---|---|
| Ashton United | 1-3 | Bangor City | |
| Chadderton | 1-5 | Hyde FC | |
| Rhyl | 1-1 | Warrington Town | |
| Tuesday 4th October 1988 | F.A. Challenge Cup 2nd Qualifying Round Replay | ||
|---|---|---|---|
| Warrington Town | 2-0 | Rhyl | |
| Saturday 8th October 1988 | F.A. Carlsberg Vase Preliminary Round | ||
|---|---|---|---|
| Atherton LR | 1-2 | Salford | |
| Bootle | 4-1 | Waterloo Dock | |
| Bridlington Town | 0-0 | Wren Rovers | |
| Burscough | 3-1 | St Dominics | |
| Chadderton | 1-3 | Maghull | |
| Clitheroe | 3-2 | Ashington | |
| Daisy Hill | 1-2 | General Chemicals | |
| Darwen | 3-2 | Langley Park Welfare | |
| Droylsden | 2-1 | Prescot Cables | |
| Formby | 2-3 | Ashton United | |
| Irlam Town | 4-3 | Skelmersdale United | |
| Knypersley Victoria | 1-3 | Vauxhall GM | |
| Leyland Motors | 4-1 | Willington | |
| Maine Road | 1-2 | Eastwood Hanley | |
| Newcastle Town | 2-2 | Glossop | |
| Tuesday 11th October 1988 | F.A. Carlsberg Vase Preliminary Round Replay | ||
|---|---|---|---|
| Glossop | 0-1 | Newcastle Town | |
| Wren Rovers | 0-3 | Bridlington Town | |
| Saturday 15th October 1988 | F.A. Challenge Cup 3rd Qualifying Round | ||
|---|---|---|---|
| Warrington Town | 1-2 | Leek Town | |
| Saturday 22nd October 1988 | F.A. Trophy 2nd Qualifying Round | ||
|---|---|---|---|
| Colwyn Bay | 2-1 | Hednesford Town | |
| Saturday 5th November 1988 | F.A. Carlsberg Vase 1st Round | ||
|---|---|---|---|
| Annfield Plain | 1-4 | Leyland Motors | |
| Ashton United | 1-0 | General Chemicals | |
| Bootle | 0-1 | Curzon Ashton | |
| Burscough | 1-6 | Rossendale United | |
| Cleator Moor Celtic | 1-2 | Clitheroe | |
| Cleator Moor Celtic | 0-1 | Clitheroe | |
| Droylsden | 1-1 | Salford | |
| (After Extra Time, 1-1 after 90 mins) | |||
| Irlam Town | 3-2 | Newcastle Town | |
| Maghull | 2-4 | Poulton Victoria | |
| Merseyside Police | 0-1 | Vauxhall GM | |
| South Shields | 4-1 | Darwen | |
| Tuesday 8th November 1988 | F.A. Carlsberg Vase 1st Round Replay | ||
|---|---|---|---|
| Salford | 1-2 | Droylsden | |
| Saturday 26th November 1988 | F.A. Carlsberg Vase 2nd Round | ||
|---|---|---|---|
| Clitheroe | 2-4 | Whickham | |
| Eastwood Hanley | 2-0 | St Helens Town | |
| Leyland Motors | 0-1 | Bridlington Town | |
| Poulton Victoria | 2-1 | Ashton United | |
| Rossendale United | 3-2 | Farsley Celtic | |
| Vauxhall GM | 1-0 | Warrington Town | |
| Saturday 3rd December 1988 | F.A. Trophy 3rd Qualifying Round | ||
|---|---|---|---|
| Corby Town | 2-2 | Colwyn Bay | |
| Tuesday 6th December 1988 | F.A. Trophy 3rd Qualifying Round Replay | ||
|---|---|---|---|
| Colwyn Bay | 2-1 | Corby Town | |
| Saturday 17th December 1988 | F.A. Carlsberg Vase 3rd Round | ||
|---|---|---|---|
| Garforth Town | 1-4 | Rossendale United | |
| Vauxhall GM | 1-2 | Holbeach United | |
| Saturday 14th January 1989 | F.A. Trophy 1st Round | ||
|---|---|---|---|
| Colwyn Bay | 1-1 | Frickley Athletic | |
| Saturday 21st January 1989 | F.A. Carlsberg Vase 4th Round | ||
|---|---|---|---|
| Rossendale United | 3-1 | Emley (original) | |
| F.A. Trophy 1st Round Replay | |||
|---|---|---|---|
| Frickley Athletic | 3-0 | Colwyn Bay |
| Saturday 11th February 1989 | F.A. Carlsberg Vase 5th Round | ||
|---|---|---|---|
| Rossendale United | 0-1 | Sudbury Town | |
