| Tuesday 15th April 2025 | Manchester Premier Cup Final | ||
| 19:45 |  Irlam v Hyde United  | Broadhurst Park | |
| Played at FC United of Manchester | |||
| Wednesday 16th April 2025 | Lancashire Challenge Trophy Final | ||
| 19:30 |  Bacup Borough v Southport  | The County Ground | |
| Played at The County Ground | |||
| Friday 18th April 2025 | Premier Division | ||
| 19:45 |  Chadderton v Litherland REMYCA  | Vestacare Stadium | |
| Played at Avro | |||
| Saturday 19th April 2025 | Premier Division | ||
| 15:00 |  Bury v Burscough  | Gigg Lane | |
| 15:00 |  Charnock Richard v Squires Gate  | Mossie Park | |
| 15:00 |  Cheadle Town v Lower Breck  | The Ground Up Solutions Stadium | |
| 15:00 |  Colne v Abbey Hey  | Haffners Stadium | |
| 15:00 |  Glossop North End v Pilkington  | The Asgard Engineering Stadium | |
| 15:00 | Irlam v FC St Helens  | The Silver St Stadium | |
| 15:00 |  Longridge Town v Prestwich Heys  | Longridge Town FC | |
| 15:00 |  Ramsbottom United v Barnoldswick Town  | Harry Williams Riverside Stadium | |
| 15:00 |  South Liverpool v AFC Liverpool  | Jericho Lane | |
| 15:00 |  Stockport Town v Padiham  | Stockport Sports Village | |
| 18:00 |  FC Isle of Man v West Didsbury & Chorlton  | The Bowl | |
| Saturday 19th April 2025 | First Division Champions Cup Final | ||
| 15:00 |  Winsford United v Atherton LR  | Barton Stadium | |
| Saturday 19th April 2025 | First Division North Play Offs SF | ||
| 15:00 |  Droylsden v Holker Old Boys  | The Butchers Arms | |
| 15:00 |  Nelson v Euxton Villa  | The Daisy Arena | |
| Saturday 19th April 2025 | First Division South Play Offs SF | ||
| 15:00 |  Abbey Hulton United v Eccleshall  | Drayton Beaumont Park | |
| 15:00 |  Stafford Town v Sandbach United  | Evans Park | |
| Monday 21st April 2025 | The Edward Case Cup Final | ||
| 15:00 | Atherton LR v Stafford Town | SMS PRO SOCCER PARK | |
| Played at FC St Helens | |||
| Saturday 26th April 2025 | First Division North Play Offs Final | ||
| 15:00 |  2nd/5th v 3rd/4th | Highest placed club | |
| Saturday 26th April 2025 | First Division South Play Offs Final | ||
| 15:00 | 2nd/5th v 3rd/4th | Highest placed club | |
| Saturday 26th April 2025 | Premier Division Play Offs | ||
| 15:00 | 2nd place v 5th place | 2nd place | |
| Saturday 3rd May 2025 | Premier Division Play Offs Final | ||
| 15:00 | 2nd/5th v 3rd/4th | Highest placed club | |
| Monday 5th May 2025 | The Macron Cup Final | ||
| 15:00 | Charnock Richard v Stafford Town | The Wham Stadium | |
| Played at Accrington Stanley | |||
| Tuesday 15th April 2025 Manchester Premier Cup Final |
|
| Irlam v Hyde United (19:45) | |
| Played at FC United of Manchester | |
| Wednesday 16th April 2025 Lancashire Challenge Trophy Final |
|
| Bacup Borough v Southport (19:30) | |
| Played at The County Ground | |
| Friday 18th April 2025 Premier Division |
|
| Chadderton v Litherland REMYCA (19:45) | |
| Played at Avro | |
| Saturday 19th April 2025 Premier Division |
| Bury v Burscough (15:00) |
| Charnock Richard v Squires Gate (15:00) |
| Cheadle Town v Lower Breck (15:00) |
| Colne v Abbey Hey (15:00) |
| Glossop North End v Pilkington (15:00) |
| Irlam v FC St Helens (15:00) |
| Longridge Town v Prestwich Heys (15:00) |
| Ramsbottom United v Barnoldswick Town (15:00) |
| South Liverpool v AFC Liverpool (15:00) |
| Stockport Town v Padiham (15:00) |
| FC Isle of Man v West Didsbury & Chorlton (18:00) |
| Saturday 19th April 2025 First Division Champions Cup Final |
| Winsford United v Atherton LR (15:00) |
| Saturday 19th April 2025 First Division North Play Offs Semi Finals |
| Droylsden v Holker Old Boys (15:00) |
| Nelson v Euxton Villa (15:00) |
| Saturday 19th April 2025 First Division South Play Offs Semi Finals |
| Abbey Hulton United v Eccleshall (15:00) |
| Stafford Town v Sandbach United (15:00) |
| Monday 21st April 2025 The Edward Case Cup Final |
|
| Atherton LR v Stafford Town (15:00) | |
| Played at FC St Helens | |
| Saturday 26th April 2025 First Division North Play Offs Final |
| 2nd/5th v 3rd/4th (15:00) |
| Saturday 26th April 2025 First Division South Play Offs Final |
| 2nd/5th v 3rd/4th (15:00) |
| Saturday 26th April 2025 Premier Division Play Offs |
| 2nd place v 5th place (15:00) |
| Saturday 26th April 2025 Premier Division Play Offs Semi Finals |
| Bury or Lower Breck v Padiham or West Didsbury & Chorlton (15:00) |
| Ramsbottom United v Padiham or West Didsbury & Chorlton (15:00) |
| Saturday 3rd May 2025 Premier Division Play Offs Final |
| 2nd/5th v 3rd/4th (15:00) |
| Monday 5th May 2025 The Macron Cup Final |
|
| Charnock Richard v Stafford Town (15:00) | |
| Played at Accrington Stanley | |
