| Tuesday 23rd December 2025 | The Edward Case Cup 2nd Round North | ||
| 19:45 |  Nelson v Daisy Hill  | The Ginge Power Stadium | |
| Played at Daisy Hill | |||
| Friday 26th December 2025 | Premier Division | ||
| 13:00 |  West Didsbury & Chorlton v Wythenshawe  | Step Places Stadium | |
| 15:00 |  Atherton LR v Burscough  | Crilly Park | |
| 15:00 |  Chadderton v Prestwich Heys  | Emplas Commercial North Stadium | |
| 15:00 |  City of Liverpool v South Liverpool  | The Community Ground | |
| 15:00 |  Euxton Villa v Charnock Richard  | Jim Fowler Memorial Ground | |
| 15:00 |  Irlam v Glossop North End  | The Silver St Stadium | |
| 15:00 |  Padiham v Barnoldswick Town  | Ruby Civil Arena | |
| 15:00 |  Pilkington v FC St Helens  | PSD Stadium | |
| Friday 26th December 2025 | First Division North | ||
| 15:00 |  Bacup Borough v Daisy Hill | Brian Boys West View Stadium | |
| 15:00 |  Darwen FC v Nelson | Multevo Group Anchor Ground | |
| 15:00 |  Droylsden v Maine Road  | The Butchers Arms | |
| 15:00 |  Holker Old Boys v Garstang  | The Handmark Engineering Stadium | |
| 15:00 |  Squires Gate v AFC Blackpool  | The Skiddle Community Stadium | |
| 15:00 |  Thornton Cleveleys v Fulwood Amateurs  | Gamble Road | |
| Friday 26th December 2025 | First Division South | ||
| 13:00 |  Ashville v Cammell Laird 1907  | Ray Parker Stadium | |
| 13:00 |  Eccleshall v Market Drayton Town  | Stoke Signage Stadium | |
| 13:30 |  Stafford Town v Foley Meir  | Evans Park | |
| 15:00 |  Allscott Heath v Telford Town  | The Giant Stadium | |
| 15:00 |  Barnton v Runcorn Town  | The Creative Hut Stadium | |
| 15:00 |  Sandbach United v Alsager Town  | Sandbach Community Football Centre | |
| 15:00 |  Shawbury United v Haughmond  | Shawbury Utd Community Sports and Recreational Centre | |
| 15:00 |  Wolverhampton Sporting Community v Wolverhampton Casuals  | Pride Park | |
| Saturday 27th December 2025 | Premier Division | ||
| 15:00 |  Cheadle Town v Abbey Hey  | The Ground Up Solutions Stadium | |
| 15:00 |  Litherland REMYCA v AFC Liverpool  | Litherland Sports Park | |
| 15:00 |  Longridge Town v Ramsbottom United  | Inglewhite Road | |
| 18:00 |  FC Isle of Man v Stockport Town  | The Bowl | |
| Saturday 27th December 2025 | First Division North | ||
| 14:00 |  MSB Woolton v Maghull  | Jericho Lane | |
| 15:00 |  Ashton Town v Ashton Athletic  | The Bartons Group Stadium | |
| 15:00 |  Steeton v Colne  | Marley Stadium | |
| Saturday 3rd January 2026 | Premier Division | ||
| 14:00 | Padiham v West Didsbury & Chorlton | Ruby Civil Arena | |
| 15:00 | AFC Liverpool v Stockport Town | Berry Street Garage Stadium | |
| 15:00 | Barnoldswick Town v Irlam | Silentnight Stadium | |
| 15:00 | Charnock Richard v Glossop North End | Mossie Park | |
| 15:00 | Cheadle Town v Euxton Villa | The Ground Up Solutions Stadium | |
| 15:00 | FC St Helens v City of Liverpool | SMS PRO SOCCER PARK | |
| 15:00 | Pilkington v Burscough | PSD Stadium | |
| 15:00 | Prestwich Heys v Longridge Town | Adie Moran Park | |
| 15:00 | Ramsbottom United v Litherland REMYCA | Harry Williams Riverside Stadium | |
| 15:00 | South Liverpool v Wythenshawe | Jericho Lane | |
| 18:00 | FC Isle of Man v Chadderton | The Bowl | |
| Saturday 3rd January 2026 | First Division North | ||
| 15:00 | AFC Blackpool v Bacup Borough | Mechanics Ground | |
| 15:00 | Ashton Athletic v Holker Old Boys | Brocstedes Park | |
| 15:00 | Daisy Hill v Ashton Town | The Ginge Power Stadium | |
| 15:00 | Droylsden v Garstang | The Butchers Arms | |
| 15:00 | Fulwood Amateurs v Darwen FC | Lightfoot Green Lane | |
| 15:00 | Maghull v Colne | DT Hughes Community Stadium | |
| 15:00 | Nelson v MSB Woolton | The Daisy Arena Little Wembley | |
| 15:00 | Steeton v Squires Gate | Marley Stadium | |
| 15:00 | Thornton Cleveleys v Maine Road | Gamble Road | |
| Saturday 3rd January 2026 | First Division South | ||
| 15:00 | Alsager Town v Ashville | Wood Park | |
| 15:00 | Cammell Laird 1907 v Stockport Georgians  | The OWS Engineering Ltd Stadium | |
| 15:00 | Eccleshall v Shawbury United | Stoke Signage Stadium | |
| 15:00 | Foley Meir v Allscott Heath | Trentham Foods Stadium | |
| 15:00 | Market Drayton Town v Sandbach United | Greenfields Sports Ground | |
| 15:00 |  New Mills v Wolverhampton Sporting Community | Church Lane | |
| 15:00 | Telford Town v Stafford Town | DRM Aggregate Arena | |
| 15:00 | Wolverhampton Casuals v Cheadle Heath Nomads  | Brinsford Stadium | |
| Tuesday 6th January 2026 | Premier Division | ||
| 19:45 | AFC Liverpool v Longridge Town | Berry Street Garage Stadium | |
| 19:45 | Barnoldswick Town v Atherton LR | Silentnight Stadium | |
| 19:45 | Charnock Richard v Chadderton | Mossie Park | |
| 19:45 | Cheadle Town v Litherland REMYCA | The Ground Up Solutions Stadium | |
| 19:45 | City of Liverpool v Prestwich Heys | The Community Ground | |
| 19:45 | Irlam v Abbey Hey | The Silver St Stadium | |
| 19:45 | Ramsbottom United v West Didsbury & Chorlton | Harry Williams Riverside Stadium | |
| 19:45 | Wythenshawe v Pilkington | Avensure Community Stadium | |
| Tuesday 6th January 2026 | First Division North | ||
| 19:45 | Ashton Athletic v Steeton | Brocstedes Park | |
| 19:45 | Colne v Nelson | Haffners Eats Stadium | |
| 19:45 | Fulwood Amateurs v Bacup Borough | Lightfoot Green Lane | |
| 20:00 | Holker Old Boys v AFC Blackpool | The Handmark Engineering Stadium | |
| Tuesday 6th January 2026 | First Division South | ||
| 19:45 | Foley Meir v Cheadle Heath Nomads | Trentham Foods Stadium | |
| 19:45 | New Mills v Runcorn Town | Church Lane | |
| 20:00 | Cammell Laird 1907 v Wolverhampton Casuals | The OWS Engineering Ltd Stadium | |
| Wednesday 7th January 2026 | First Division South | ||
| 20:00 | Eccleshall v Stockport Georgians | Stoke Signage Stadium | |
| 20:00 | Telford Town v Ashville | DRM Aggregate Arena | |
| Saturday 10th January 2026 | Premier Division | ||
| 15:00 | Abbey Hey v City of Liverpool | The Abbey Stadium | |
| 15:00 | Atherton LR v Padiham | Crilly Park | |
| 15:00 | Euxton Villa v Chadderton | Jim Fowler Memorial Ground | |
| 15:00 | FC St Helens v West Didsbury & Chorlton | SMS PRO SOCCER PARK | |
| 15:00 | Glossop North End v Barnoldswick Town | The Asgard Engineering Stadium | |
| 15:00 | Irlam v South Liverpool | The Silver St Stadium | |
| 15:00 | Longridge Town v Cheadle Town | Inglewhite Road | |
| 15:00 | Prestwich Heys v AFC Liverpool | Adie Moran Park | |
| 15:00 | Stockport Town v Ramsbottom United | Stockport Sports Village | |
| 15:00 | Wythenshawe v Litherland REMYCA | Avensure Community Stadium | |
| 18:00 | FC Isle of Man v Burscough | The Bowl | |
| Saturday 10th January 2026 | First Division North | ||
| 15:00 | Bacup Borough v Ashton Athletic | Brian Boys West View Stadium | |
| 15:00 | Colne v Holker Old Boys | Haffners Eats Stadium | |
| 15:00 | Darwen FC v Droylsden | Multevo Group Anchor Ground | |
| 15:00 | Garstang v Daisy Hill | The Riverside | |
| 15:00 | Maghull v AFC Blackpool | DT Hughes Community Stadium | |
| 15:00 | Maine Road v Nelson | Brantingham Road | |
| 15:00 | MSB Woolton v Thornton Cleveleys | Jericho Lane | |
| Saturday 10th January 2026 | First Division South | ||
| 15:00 | Allscott Heath v Eccleshall | The Giant Stadium | |
| 15:00 | Barnton v Alsager Town | The Creative Hut Stadium | |
| 15:00 | Cammell Laird 1907 v Market Drayton Town | The OWS Engineering Ltd Stadium | |
| 15:00 | Cheadle Heath Nomads v Wolverhampton Sporting Community | Ideal Building Systems Stadium | |
| 15:00 | Foley Meir v Ashville | Trentham Foods Stadium | |
| 15:00 | Haughmond v Stockport Georgians | Sundorne Sports Village | |
| 15:00 | New Mills v Sandbach United | Church Lane | |
| 15:00 | Runcorn Town v Shawbury United | Viridor Community Stadium | |
| 15:00 | Wolverhampton Casuals v Stafford Town | Brinsford Stadium | |
| Tuesday 23rd December 2025 The Edward Case Cup 2nd Round North |
|
| Nelson v Daisy Hill (19:45) | |
| Played at Daisy Hill | |
| Friday 26th December 2025 Premier Division |
| West Didsbury & Chorlton v Wythenshawe (13:00) |
| Atherton LR v Burscough (15:00) |
| Chadderton v Prestwich Heys (15:00) |
| City of Liverpool v South Liverpool (15:00) |
| Euxton Villa v Charnock Richard (15:00) |
| Irlam v Glossop North End (15:00) |
| Padiham v Barnoldswick Town (15:00) |
| Pilkington v FC St Helens (15:00) |
| Friday 26th December 2025 First Division North |
| Bacup Borough v Daisy Hill (15:00) |
| Darwen FC v Nelson (15:00) |
| Droylsden v Maine Road (15:00) |
| Holker Old Boys v Garstang (15:00) |
| Squires Gate v AFC Blackpool (15:00) |
| Thornton Cleveleys v Fulwood Amateurs (15:00) |
| Friday 26th December 2025 First Division South |
| Ashville v Cammell Laird 1907 (13:00) |
| Eccleshall v Market Drayton Town (13:00) |
| Stafford Town v Foley Meir (13:30) |
| Allscott Heath v Telford Town (15:00) |
| Barnton v Runcorn Town (15:00) |
| Sandbach United v Alsager Town (15:00) |
| Shawbury United v Haughmond (15:00) |
| Wolverhampton Sporting Community v Wolverhampton Casuals (15:00) |
| Saturday 27th December 2025 Premier Division |
| Cheadle Town v Abbey Hey (15:00) |
| Litherland REMYCA v AFC Liverpool (15:00) |
| Longridge Town v Ramsbottom United (15:00) |
| FC Isle of Man v Stockport Town (18:00) |
| Saturday 27th December 2025 First Division North |
| MSB Woolton v Maghull (14:00) |
| Ashton Town v Ashton Athletic (15:00) |
| Steeton v Colne (15:00) |
| Saturday 3rd January 2026 Premier Division |
| Padiham v West Didsbury & Chorlton (14:00) |
| AFC Liverpool v Stockport Town (15:00) |
| Barnoldswick Town v Irlam (15:00) |
| Charnock Richard v Glossop North End (15:00) |
| Cheadle Town v Euxton Villa (15:00) |
| FC St Helens v City of Liverpool (15:00) |
| Pilkington v Burscough (15:00) |
| Prestwich Heys v Longridge Town (15:00) |
| Ramsbottom United v Litherland REMYCA (15:00) |
| South Liverpool v Wythenshawe (15:00) |
| FC Isle of Man v Chadderton (18:00) |
| Saturday 3rd January 2026 First Division North |
| AFC Blackpool v Bacup Borough (15:00) |
| Ashton Athletic v Holker Old Boys (15:00) |
| Daisy Hill v Ashton Town (15:00) |
| Droylsden v Garstang (15:00) |
| Fulwood Amateurs v Darwen FC (15:00) |
| Maghull v Colne (15:00) |
| Nelson v MSB Woolton (15:00) |
| Steeton v Squires Gate (15:00) |
| Thornton Cleveleys v Maine Road (15:00) |
| Saturday 3rd January 2026 First Division South |
| Alsager Town v Ashville (15:00) |
| Cammell Laird 1907 v Stockport Georgians (15:00) |
| Eccleshall v Shawbury United (15:00) |
| Foley Meir v Allscott Heath (15:00) |
| Market Drayton Town v Sandbach United (15:00) |
| New Mills v Wolverhampton Sporting Community (15:00) |
| Telford Town v Stafford Town (15:00) |
| Wolverhampton Casuals v Cheadle Heath Nomads (15:00) |
| Tuesday 6th January 2026 Premier Division |
| AFC Liverpool v Longridge Town (19:45) |
| Barnoldswick Town v Atherton LR (19:45) |
| Charnock Richard v Chadderton (19:45) |
| Cheadle Town v Litherland REMYCA (19:45) |
| City of Liverpool v Prestwich Heys (19:45) |
| Irlam v Abbey Hey (19:45) |
| Ramsbottom United v West Didsbury & Chorlton (19:45) |
| Wythenshawe v Pilkington (19:45) |
| Tuesday 6th January 2026 First Division North |
| Ashton Athletic v Steeton (19:45) |
| Colne v Nelson (19:45) |
| Fulwood Amateurs v Bacup Borough (19:45) |
| Holker Old Boys v AFC Blackpool (20:00) |
| Tuesday 6th January 2026 First Division South |
| Foley Meir v Cheadle Heath Nomads (19:45) |
| New Mills v Runcorn Town (19:45) |
| Cammell Laird 1907 v Wolverhampton Casuals (20:00) |
| Wednesday 7th January 2026 First Division South |
| Eccleshall v Stockport Georgians (20:00) |
| Telford Town v Ashville (20:00) |
| Saturday 10th January 2026 Premier Division |
| Abbey Hey v City of Liverpool (15:00) |
| Atherton LR v Padiham (15:00) |
| Euxton Villa v Chadderton (15:00) |
| FC St Helens v West Didsbury & Chorlton (15:00) |
| Glossop North End v Barnoldswick Town (15:00) |
| Irlam v South Liverpool (15:00) |
| Longridge Town v Cheadle Town (15:00) |
| Prestwich Heys v AFC Liverpool (15:00) |
| Stockport Town v Ramsbottom United (15:00) |
| Wythenshawe v Litherland REMYCA (15:00) |
| FC Isle of Man v Burscough (18:00) |
| Saturday 10th January 2026 First Division North |
| Bacup Borough v Ashton Athletic (15:00) |
| Colne v Holker Old Boys (15:00) |
| Darwen FC v Droylsden (15:00) |
| Garstang v Daisy Hill (15:00) |
| Maghull v AFC Blackpool (15:00) |
| Maine Road v Nelson (15:00) |
| MSB Woolton v Thornton Cleveleys (15:00) |
| Saturday 10th January 2026 First Division South |
| Allscott Heath v Eccleshall (15:00) |
| Barnton v Alsager Town (15:00) |
| Cammell Laird 1907 v Market Drayton Town (15:00) |
| Cheadle Heath Nomads v Wolverhampton Sporting Community (15:00) |
| Foley Meir v Ashville (15:00) |
| Haughmond v Stockport Georgians (15:00) |
| New Mills v Sandbach United (15:00) |
| Runcorn Town v Shawbury United (15:00) |
| Wolverhampton Casuals v Stafford Town (15:00) |
