| Monday 6th February 2023 | First Division South | ||
| 19:45 |  Maine Road v Cheadle Town  | Brantingham Road | |
| Tuesday 7th February 2023 | Premier Division | ||
| 19:45 |  Ashton Athletic v Bury AFC  | Brocstedes Park | |
| 19:45 |  Vauxhall Motors v Northwich Victoria  | The vanEupen Arena | |
| 20:00 |  Kendal Town v Avro  | J Robs Ground Maintenance Stadium | |
| Tuesday 7th February 2023 | First Division North | ||
| 19:45 |  Ashton Town v Pilkington  | Hebs Group Stadium | |
| 19:45 |  Chadderton v FC St Helens  | The Falcon Fire Stadium | |
| 19:45 |  Euxton Villa v Ilkley Town  | Jim Fowler Memorial Ground | |
| 19:45 |  Nelson v Atherton LR  | Little Wembley | |
| 20:00 |  Cleator Moor Celtic v AFC Blackpool  | McGrath Park | |
| Tuesday 7th February 2023 | First Division South | ||
| 19:45 |  Abbey Hey v Foley Meir  | The Abbey Stadium | |
| 19:45 |  Abbey Hulton United v Cammell Laird 1907  | Drayton Beaumont Park | |
| 19:45 |  Alsager Town v Rocester  | Woodpark Stadium | |
| 19:45 |  Stockport Georgians v Ashville  | Cromley Road | |
| Tuesday 7th February 2023 | Lancashire Challenge Trophy 2nd Rnd | ||
| 19:45 |  Padiham v Charnock Richard  | Ruby Civil Arena | |
| Tuesday 7th February 2023 | Manchester Premier Cup QF | ||
| 19:45 |  Ashton United v Wythenshawe Town  | Hurst Cross | |
| Wednesday 8th February 2023 | Premier Division | ||
| 19:45 |  AFC Liverpool v Longridge Town  | The Marine Travel Arena | |
| 20:00 |  Litherland REMYCA v Barnoldswick Town  | Litherland Sports Park | |
| 20:00 |  Squires Gate v FC Isle of Man  | The Brian Addison Stadium | |
| Wednesday 8th February 2023 | First Division North | ||
| 20:00 |  Bacup Borough v Holker Old Boys  | Brian Boys West View Stadium | |
| Wednesday 8th February 2023 | First Division South | ||
| 20:00 |  Eccleshall v Wythenshawe Amateurs  | Pershall Park | |
| Friday 10th February 2023 | First Division North | ||
| 19:45 |  South Liverpool v Pilkington | Jericho Lane | |
| Saturday 11th February 2023 | The Isuzu FA Vase 5th Rnd | ||
| 15:00 |  AFC Wulfrunians v Congleton Town  | Castlecroft Stadium | |
| 15:00 |  Coventry Sphinx v West Didsbury & Chorlton  | Sphinx Sports & Leisure Club | |
| Saturday 11th February 2023 | Premier Division | ||
| 15:00 | AFC Liverpool v Ashton Athletic | The Marine Travel Arena | |
| 15:00 | Avro v Squires Gate | Vestacare Stadium | |
| 15:00 |  Burscough v Litherland REMYCA | The Community Ground | |
| 15:00 | Kendal Town v Lower Breck  | J Robs Ground Maintenance Stadium | |
| 15:00 | Longridge Town v Charnock Richard | The Recycling Lives Ground | |
| 15:00 | Northwich Victoria v Winsford United  | Wincham Park | |
| 15:00 | Vauxhall Motors v Barnoldswick Town | The vanEupen Arena | |
| 15:00 | Wythenshawe Town v Padiham | Ericstan Park | |
| 18:00 | FC Isle of Man v Irlam  | The Bowl | |
| Saturday 11th February 2023 | First Division North | ||
| 15:00 | Ashton Town v Euxton Villa | Hebs Group Stadium | |
| 15:00 | Atherton LR v Runcorn Town  | Crilly Park | |
| 15:00 | Cleator Moor Celtic v Chadderton | McGrath Park | |
| 15:00 |  Daisy Hill v Steeton  | New Sirs | |
| 15:00 |  Darwen FC v Garstang  | WEC Group Anchor Ground | |
| 15:00 | FC St Helens v AFC Blackpool | Windleshaw Sports Ground | |
| 15:00 | Ilkley Town v Bacup Borough | MPM Stadium | |
| 15:00 | Nelson v Holker Old Boys | Little Wembley | |
| Saturday 11th February 2023 | First Division South | ||
| 15:00 | Abbey Hey v Brocton  | The Abbey Stadium | |
| 15:00 | Abbey Hulton United v Wythenshawe Amateurs | Drayton Beaumont Park | |
| 15:00 | Ashville v Sandbach United  | Villa Park | |
| 15:00 | Cheadle Town v Cammell Laird 1907 | Park Road Stadium | |
| 15:00 | Eccleshall v Foley Meir | Pershall Park | |
| 15:00 |  Ellesmere Rangers v Barnton  | Beech Grove Stadium | |
| 15:00 | Maine Road v New Mills  | Brantingham Road | |
| 15:00 | Rocester v Cheadle Heath Nomads  | Hillsfield | |
| 15:00 |  Stafford Town v Stockport Town  | Evans Park | |
| 15:00 | Stockport Georgians v Alsager Town | Cromley Road | |
| Monday 13th February 2023 | Premier Division | ||
| 19:45 | Winsford United v Vauxhall Motors | Barton Stadium | |
| Tuesday 14th February 2023 | Premier Division | ||
| 19:45 | Charnock Richard v Irlam | Mossie Park | |
| 19:45 | Congleton Town v Bury AFC | The Cleric Stadium | |
| 19:45 | Kendal Town v Longridge Town | J Robs Ground Maintenance Stadium | |
| 19:45 | West Didsbury & Chorlton v Northwich Victoria | Step Places Stadium | |
| Tuesday 14th February 2023 | First Division North | ||
| 19:45 | AFC Blackpool v South Liverpool | Mechanics Ground | |
| 19:45 | Bacup Borough v FC St Helens | Brian Boys West View Stadium | |
| 19:45 | Chadderton v Ilkley Town | The Falcon Fire Stadium | |
| 20:00 | Ashton Town v Holker Old Boys | Hebs Group Stadium | |
| Tuesday 14th February 2023 | First Division South | ||
| 19:45 | Abbey Hey v Rocester | The Abbey Stadium | |
| 19:45 | Abbey Hulton United v Ashville | Drayton Beaumont Park | |
| 19:45 | Foley Meir v Alsager Town | McIntosh Arena | |
| 20:00 | Cheadle Heath Nomads v Eccleshall | The Heath | |
| 20:00 | Ellesmere Rangers v New Mills | Beech Grove Stadium | |
| Tuesday 14th February 2023 | Liverpool Senior Cup QF | ||
| 19:30 |  Southport v AFC Liverpool | Merseyrail Community Stadium | |
| Tuesday 14th February 2023 | Wirral Senior Cup 2nd Rnd | ||
| 19:30 | Cammell Laird 1907 v Higher Bebington Kelma  | Prabhu Ventures Ltd Arena | |
| Wednesday 15th February 2023 | Premier Division | ||
| 19:45 | Barnoldswick Town v Squires Gate | Silentnight Stadium | |
| 19:45 | Padiham v Prestwich Heys  | Ruby Civil Arena | |
| Wednesday 15th February 2023 | First Division North | ||
| 20:00 | Darwen FC v Cleator Moor Celtic | WEC Group Anchor Ground | |
| 20:00 | Garstang v Pilkington | The Riverside | |
| Saturday 18th February 2023 | The Macron Cup QF | ||
| 15:00 | Congleton Town v Northwich Victoria | The Cleric Stadium | |
| 15:00 | FC St Helens v Squires Gate | Windleshaw Sports Ground | |
| Saturday 18th February 2023 | Premier Division | ||
| 15:00 | Ashton Athletic v FC Isle of Man | Brocstedes Park | |
| 15:00 | Barnoldswick Town v Bury AFC | Silentnight Stadium | |
| 15:00 | Irlam v Burscough | The RG3 Digital Stadium | |
| 15:00 | Padiham v Kendal Town | Ruby Civil Arena | |
| 15:00 | Vauxhall Motors v Charnock Richard | The vanEupen Arena | |
| 15:00 | West Didsbury & Chorlton v AFC Liverpool | Step Places Stadium | |
| 15:00 | Winsford United v Prestwich Heys | Barton Stadium | |
| Saturday 18th February 2023 | First Division North | ||
| 15:00 | AFC Blackpool v Runcorn Town | Mechanics Ground | |
| 15:00 | Atherton LR v Ilkley Town | Crilly Park | |
| 15:00 | Bacup Borough v Ashton Town | Brian Boys West View Stadium | |
| 15:00 | Cleator Moor Celtic v Nelson | McGrath Park | |
| 15:00 | Garstang v Daisy Hill | The Riverside | |
| 15:00 | Pilkington v Chadderton | The Arcoframe Stadium | |
| 15:00 | Steeton v Darwen FC | Marley Stadium | |
| Saturday 18th February 2023 | First Division South | ||
| 14:00 | Wythenshawe Amateurs v Ellesmere Rangers | Selco Builders Warehouse Community Stadium | |
| 15:00 | Ashville v Stafford Town | Villa Park | |
| 15:00 | Barnton v Stockport Georgians | Townfield | |
| 15:00 | Brocton v Eccleshall | Silkmore Lane Sports Ground | |
| 15:00 | Cheadle Heath Nomads v Alsager Town | The Heath | |
| 15:00 | Foley Meir v Abbey Hey | McIntosh Arena | |
| 15:00 | New Mills v Cheadle Town | Church Lane | |
| 15:00 | Rocester v Maine Road | Hillsfield | |
| 15:00 | Sandbach United v Abbey Hulton United | Sandbach Community Football Centre | |
| 15:00 | Stockport Town v Cammell Laird 1907 | Stockport Sports Village | |
| Monday 20th February 2023 | Premier Division | ||
| 19:45 | Winsford United v Kendal Town | Barton Stadium | |
| Monday 20th February 2023 | First Division South | ||
| 19:45 | Maine Road v Cheadle Heath Nomads | Brantingham Road | |
| Tuesday 21st February 2023 | Premier Division | ||
| 19:45 | Ashton Athletic v Squires Gate | Brocstedes Park | |
| 19:45 | Barnoldswick Town v Northwich Victoria | Silentnight Stadium | |
| 19:45 | Bury AFC v West Didsbury & Chorlton | Neuven Stadium | |
| 19:45 | Prestwich Heys v Congleton Town | Adie Moran Park | |
| 19:45 | Wythenshawe Town v Litherland REMYCA | Ericstan Park | |
| Tuesday 21st February 2023 | First Division North | ||
| 19:45 | Holker Old Boys v Euxton Villa | The Handmark Engineering Stadium | |
| 19:45 | Nelson v FC St Helens | Little Wembley | |
| 20:00 | AFC Blackpool v Steeton | Mechanics Ground | |
| 20:00 | Ashton Town v Cleator Moor Celtic | Hebs Group Stadium | |
| 20:00 | Ilkley Town v Pilkington | MPM Stadium | |
| Tuesday 21st February 2023 | First Division South | ||
| 19:45 | Abbey Hulton United v Stockport Town | Drayton Beaumont Park | |
| 19:45 | Alsager Town v Cheadle Town | Woodpark Stadium | |
| 19:45 | Cheadle Heath Nomads v New Mills | The Heath | |
| 19:45 | Ellesmere Rangers v Stafford Town | Beech Grove Stadium | |
| 19:45 | Foley Meir v Brocton | McIntosh Arena | |
| 19:45 | Stockport Georgians v Wythenshawe Amateurs | Cromley Road | |
| 20:00 | Ashville v Eccleshall | Villa Park | |
| Wednesday 22nd February 2023 | First Division North | ||
| 20:00 | Bacup Borough v Runcorn Town | Brian Boys West View Stadium | |
| Wednesday 22nd February 2023 | Staffordshire Senior Cup QF | ||
| 19:45 | Rocester v Port Vale  | Hillsfield | |
| Saturday 25th February 2023 | The Edward Case Cup QF | ||
| 15:00 | Bacup Borough v Pilkington | Brian Boys West View Stadium | |
| 15:00 | Chadderton v Abbey Hey | The Falcon Fire Stadium | |
| 15:00 | South Liverpool v Abbey Hulton United | Jericho Lane | |
| 15:00 | Stockport Town v Ellesmere Rangers | Stockport Sports Village | |
| Saturday 25th February 2023 | Premier Division | ||
| 14:00 | Prestwich Heys v FC Isle of Man | Adie Moran Park | |
| 15:00 | Ashton Athletic v Lower Breck | Brocstedes Park | |
| 15:00 | Avro v Irlam | Vestacare Stadium | |
| 15:00 | Burscough v Bury AFC | The Community Ground | |
| 15:00 | Congleton Town v Vauxhall Motors | The Cleric Stadium | |
| 15:00 | Kendal Town v AFC Liverpool | J Robs Ground Maintenance Stadium | |
| 15:00 | Longridge Town v Winsford United | The Recycling Lives Ground | |
| 15:00 | Northwich Victoria v Barnoldswick Town | Wincham Park | |
| 15:00 | Padiham v Charnock Richard | Ruby Civil Arena | |
| 15:00 | Squires Gate v Litherland REMYCA | The Brian Addison Stadium | |
| 15:00 | West Didsbury & Chorlton v Wythenshawe Town | Step Places Stadium | |
| Saturday 25th February 2023 | First Division North | ||
| 15:00 | Atherton LR v Holker Old Boys | Crilly Park | |
| 15:00 | Darwen FC v AFC Blackpool | WEC Group Anchor Ground | |
| 15:00 | Euxton Villa v Garstang | Jim Fowler Memorial Ground | |
| 15:00 | FC St Helens v Cleator Moor Celtic | Windleshaw Sports Ground | |
| 15:00 | Runcorn Town v Daisy Hill | Viridor Community Stadium | |
| 15:00 | Steeton v Nelson | Marley Stadium | |
| Saturday 25th February 2023 | First Division South | ||
| 14:00 | Cammell Laird 1907 v Rocester | Prabhu Ventures Ltd Arena | |
| 15:00 | Alsager Town v Wythenshawe Amateurs | Woodpark Stadium | |
| 15:00 | Cheadle Heath Nomads v Brocton | The Heath | |
| 15:00 | Eccleshall v Cheadle Town | Pershall Park | |
| 15:00 | Maine Road v Ashville | Brantingham Road | |
| 15:00 | Sandbach United v New Mills | Sandbach Community Football Centre | |
| 15:00 | Stockport Georgians v Foley Meir | Cromley Road | |
| Monday 6th February 2023 First Division South |
| Maine Road v Cheadle Town (19:45) |
| Tuesday 7th February 2023 Premier Division |
| Ashton Athletic v Bury AFC (19:45) |
| Vauxhall Motors v Northwich Victoria (19:45) |
| Kendal Town v Avro (20:00) |
| Tuesday 7th February 2023 First Division North |
| Ashton Town v Pilkington (19:45) |
| Chadderton v FC St Helens (19:45) |
| Euxton Villa v Ilkley Town (19:45) |
| Nelson v Atherton LR (19:45) |
| Cleator Moor Celtic v AFC Blackpool (20:00) |
| Tuesday 7th February 2023 First Division South |
| Abbey Hey v Foley Meir (19:45) |
| Abbey Hulton United v Cammell Laird 1907 (19:45) |
| Alsager Town v Rocester (19:45) |
| Stockport Georgians v Ashville (19:45) |
| Tuesday 7th February 2023 Lancashire Challenge Trophy 2nd Round |
| Padiham v Charnock Richard (19:45) |
| Tuesday 7th February 2023 Manchester Premier Cup Quarter Finals |
| Ashton United v Wythenshawe Town (19:45) |
| Wednesday 8th February 2023 Premier Division |
| AFC Liverpool v Longridge Town (19:45) |
| Litherland REMYCA v Barnoldswick Town (20:00) |
| Squires Gate v FC Isle of Man (20:00) |
| Wednesday 8th February 2023 First Division North |
| Bacup Borough v Holker Old Boys (20:00) |
| Wednesday 8th February 2023 First Division South |
| Eccleshall v Wythenshawe Amateurs (20:00) |
| Friday 10th February 2023 First Division North |
| South Liverpool v Pilkington (19:45) |
| Saturday 11th February 2023 The Isuzu FA Vase 5th Round |
| AFC Wulfrunians v Congleton Town (15:00) |
| Coventry Sphinx v West Didsbury & Chorlton (15:00) |
| Saturday 11th February 2023 Premier Division |
| AFC Liverpool v Ashton Athletic (15:00) |
| Avro v Squires Gate (15:00) |
| Burscough v Litherland REMYCA (15:00) |
| Kendal Town v Lower Breck (15:00) |
| Longridge Town v Charnock Richard (15:00) |
| Northwich Victoria v Winsford United (15:00) |
| Vauxhall Motors v Barnoldswick Town (15:00) |
| Wythenshawe Town v Padiham (15:00) |
| FC Isle of Man v Irlam (18:00) |
| Saturday 11th February 2023 First Division North |
| Ashton Town v Euxton Villa (15:00) |
| Atherton LR v Runcorn Town (15:00) |
| Cleator Moor Celtic v Chadderton (15:00) |
| Daisy Hill v Steeton (15:00) |
| Darwen FC v Garstang (15:00) |
| FC St Helens v AFC Blackpool (15:00) |
| Ilkley Town v Bacup Borough (15:00) |
| Nelson v Holker Old Boys (15:00) |
| Saturday 11th February 2023 First Division South |
| Abbey Hey v Brocton (15:00) |
| Abbey Hulton United v Wythenshawe Amateurs (15:00) |
| Ashville v Sandbach United (15:00) |
| Cheadle Town v Cammell Laird 1907 (15:00) |
| Eccleshall v Foley Meir (15:00) |
| Ellesmere Rangers v Barnton (15:00) |
| Maine Road v New Mills (15:00) |
| Rocester v Cheadle Heath Nomads (15:00) |
| Stafford Town v Stockport Town (15:00) |
| Stockport Georgians v Alsager Town (15:00) |
| Monday 13th February 2023 Premier Division |
| Winsford United v Vauxhall Motors (19:45) |
| Tuesday 14th February 2023 Premier Division |
| Charnock Richard v Irlam (19:45) |
| Congleton Town v Bury AFC (19:45) |
| Kendal Town v Longridge Town (19:45) |
| West Didsbury & Chorlton v Northwich Victoria (19:45) |
| Tuesday 14th February 2023 First Division North |
| AFC Blackpool v South Liverpool (19:45) |
| Bacup Borough v FC St Helens (19:45) |
| Chadderton v Ilkley Town (19:45) |
| Ashton Town v Holker Old Boys (20:00) |
| Tuesday 14th February 2023 First Division South |
| Abbey Hey v Rocester (19:45) |
| Abbey Hulton United v Ashville (19:45) |
| Foley Meir v Alsager Town (19:45) |
| Cheadle Heath Nomads v Eccleshall (20:00) |
| Ellesmere Rangers v New Mills (20:00) |
| Tuesday 14th February 2023 Liverpool Senior Cup Quarter Finals |
| Southport v AFC Liverpool (19:30) |
| Tuesday 14th February 2023 Wirral Senior Cup 2nd Round |
| Cammell Laird 1907 v Higher Bebington Kelma (19:30) |
| Wednesday 15th February 2023 Premier Division |
| Barnoldswick Town v Squires Gate (19:45) |
| Padiham v Prestwich Heys (19:45) |
| Wednesday 15th February 2023 First Division North |
| Darwen FC v Cleator Moor Celtic (20:00) |
| Garstang v Pilkington (20:00) |
| Saturday 18th February 2023 The Macron Cup Quarter Finals |
| Congleton Town v Northwich Victoria (15:00) |
| FC St Helens v Squires Gate (15:00) |
| Saturday 18th February 2023 Premier Division |
| Ashton Athletic v FC Isle of Man (15:00) |
| Barnoldswick Town v Bury AFC (15:00) |
| Irlam v Burscough (15:00) |
| Padiham v Kendal Town (15:00) |
| Vauxhall Motors v Charnock Richard (15:00) |
| West Didsbury & Chorlton v AFC Liverpool (15:00) |
| Winsford United v Prestwich Heys (15:00) |
| Saturday 18th February 2023 First Division North |
| AFC Blackpool v Runcorn Town (15:00) |
| Atherton LR v Ilkley Town (15:00) |
| Bacup Borough v Ashton Town (15:00) |
| Cleator Moor Celtic v Nelson (15:00) |
| Garstang v Daisy Hill (15:00) |
| Pilkington v Chadderton (15:00) |
| Steeton v Darwen FC (15:00) |
| Saturday 18th February 2023 First Division South |
| Wythenshawe Amateurs v Ellesmere Rangers (14:00) |
| Ashville v Stafford Town (15:00) |
| Barnton v Stockport Georgians (15:00) |
| Brocton v Eccleshall (15:00) |
| Cheadle Heath Nomads v Alsager Town (15:00) |
| Foley Meir v Abbey Hey (15:00) |
| New Mills v Cheadle Town (15:00) |
| Rocester v Maine Road (15:00) |
| Sandbach United v Abbey Hulton United (15:00) |
| Stockport Town v Cammell Laird 1907 (15:00) |
| Monday 20th February 2023 Premier Division |
| Winsford United v Kendal Town (19:45) |
| Monday 20th February 2023 First Division South |
| Maine Road v Cheadle Heath Nomads (19:45) |
| Tuesday 21st February 2023 Premier Division |
| Ashton Athletic v Squires Gate (19:45) |
| Barnoldswick Town v Northwich Victoria (19:45) |
| Bury AFC v West Didsbury & Chorlton (19:45) |
| Prestwich Heys v Congleton Town (19:45) |
| Wythenshawe Town v Litherland REMYCA (19:45) |
| Tuesday 21st February 2023 First Division North |
| Holker Old Boys v Euxton Villa (19:45) |
| Nelson v FC St Helens (19:45) |
| AFC Blackpool v Steeton (20:00) |
| Ashton Town v Cleator Moor Celtic (20:00) |
| Ilkley Town v Pilkington (20:00) |
| Tuesday 21st February 2023 First Division South |
| Abbey Hulton United v Stockport Town (19:45) |
| Alsager Town v Cheadle Town (19:45) |
| Cheadle Heath Nomads v New Mills (19:45) |
| Ellesmere Rangers v Stafford Town (19:45) |
| Foley Meir v Brocton (19:45) |
| Stockport Georgians v Wythenshawe Amateurs (19:45) |
| Ashville v Eccleshall (20:00) |
| Wednesday 22nd February 2023 First Division North |
| Bacup Borough v Runcorn Town (20:00) |
| Wednesday 22nd February 2023 Staffordshire Senior Cup Quarter Finals |
| Rocester v Port Vale (19:45) |
| Saturday 25th February 2023 The Edward Case Cup Quarter Finals |
| Bacup Borough v Pilkington (15:00) |
| Chadderton v Abbey Hey (15:00) |
| South Liverpool v Abbey Hulton United (15:00) |
| Stockport Town v Ellesmere Rangers (15:00) |
| Saturday 25th February 2023 Premier Division |
| Prestwich Heys v FC Isle of Man (14:00) |
| Ashton Athletic v Lower Breck (15:00) |
| Avro v Irlam (15:00) |
| Burscough v Bury AFC (15:00) |
| Congleton Town v Vauxhall Motors (15:00) |
| Kendal Town v AFC Liverpool (15:00) |
| Longridge Town v Winsford United (15:00) |
| Northwich Victoria v Barnoldswick Town (15:00) |
| Padiham v Charnock Richard (15:00) |
| Squires Gate v Litherland REMYCA (15:00) |
| West Didsbury & Chorlton v Wythenshawe Town (15:00) |
| Saturday 25th February 2023 First Division North |
| Atherton LR v Holker Old Boys (15:00) |
| Darwen FC v AFC Blackpool (15:00) |
| Euxton Villa v Garstang (15:00) |
| FC St Helens v Cleator Moor Celtic (15:00) |
| Runcorn Town v Daisy Hill (15:00) |
| Steeton v Nelson (15:00) |
| Saturday 25th February 2023 First Division South |
| Cammell Laird 1907 v Rocester (14:00) |
| Alsager Town v Wythenshawe Amateurs (15:00) |
| Cheadle Heath Nomads v Brocton (15:00) |
| Eccleshall v Cheadle Town (15:00) |
| Maine Road v Ashville (15:00) |
| Sandbach United v New Mills (15:00) |
| Stockport Georgians v Foley Meir (15:00) |
