| Saturday 26th July 2025 | Premier Division | ||
| 15:00 |  AFC Liverpool v Irlam  | Berry Street Garage Stadium | |
| 15:00 |  Burscough v Abbey Hey  | The Community Ground | |
| 15:00 |  Chadderton v Charnock Richard  | Emplas Commercial North Stadium | |
| 15:00 |  Cheadle Town v Barnoldswick Town  | The Ground Up Solutions Stadium | |
| 15:00 |  Euxton Villa v Prestwich Heys  | Jim Fowler Memorial Ground | |
| 15:00 |  Glossop North End v City of Liverpool  | The Asgard Engineering Stadium | |
| 15:00 |  Longridge Town v FC St Helens  | Inglewhite Road | |
| 15:00 |  Padiham v Wythenshawe  | Ruby Civil Arena | |
| 15:00 |  Ramsbottom United v Atherton LR  | Harry Williams Riverside Stadium | |
| 15:00 |  South Liverpool v Stockport Town  | Jericho Lane | |
| 15:00 |  West Didsbury & Chorlton v Pilkington  | Step Places Stadium | |
| 18:00 |  FC Isle of Man v Litherland REMYCA  | The Bowl | |
| Saturday 26th July 2025 | First Division North | ||
| 15:00 |  Colne v Ashton Town  | Haffners Eats Stadium | |
| 15:00 |  Daisy Hill v Ashton Athletic  | The Ginge Power Stadium | |
| 15:00 |  Darwen FC v Thornton Cleveleys  | Multevo Group Anchor Ground | |
| 15:00 |  Droylsden v AFC Blackpool  | The Butchers Arms | |
| 15:00 |  Holker Old Boys v Nelson  | The Handmark Engineering Stadium | |
| 15:00 |  Maghull v Squires Gate  | DT Hughes Community Stadium | |
| 15:00 |  Maine Road v Garstang  | Brantingham Road | |
| 15:00 |  Steeton v Fulwood Amateurs  | Marley Stadium | |
| Saturday 26th July 2025 | First Division South | ||
| 15:00 |  Allscott Heath v Cheadle Heath Nomads  | The Giant Stadium | |
| 15:00 |  Ashville v Wolverhampton Casuals  | Ray Parker Stadium | |
| 15:00 |  Barnton v Haughmond  | The Creative Hut Stadium | |
| 15:00 |  Foley Meir v Telford Town  | Trentham Foods Stadium | |
| 15:00 |  New Mills v Alsager Town  | Church Lane | |
| 15:00 |  Runcorn Town v Market Drayton Town  | Viridor Community Stadium | |
| 15:00 |  Shawbury United v Cammell Laird 1907  | Shawbury Utd Community Sports and Recreational Centre | |
| 15:00 |  Stafford Town v Eccleshall  | Evans Park | |
| 15:00 |  Wolverhampton Sporting Community v Stockport Georgians  | Pride Park | |
| Tuesday 29th July 2025 | Premier Division | ||
| 19:45 | Abbey Hey v Stockport Town | The Abbey Stadium | |
| 19:45 | Atherton LR v South Liverpool | Crilly Park | |
| 19:45 | Barnoldswick Town v Charnock Richard | Silentnight Stadium | |
| 19:45 | Burscough v AFC Liverpool | The Community Ground | |
| 19:45 | Cheadle Town v Ramsbottom United | The Ground Up Solutions Stadium | |
| 19:45 | FC St Helens v FC Isle of Man | SMS PRO SOCCER PARK | |
| 19:45 | Glossop North End v West Didsbury & Chorlton | The Asgard Engineering Stadium | |
| 19:45 | Irlam v Pilkington | The Silver St Stadium | |
| 19:45 | Prestwich Heys v Padiham | Adie Moran Park | |
| 19:45 | Wythenshawe v Chadderton | Hollyhedge Park Community Stadium | |
| 20:00 | Euxton Villa v Longridge Town | Jim Fowler Memorial Ground | |
| Tuesday 29th July 2025 | First Division South | ||
| 19:45 | Ashville v Runcorn Town | Ray Parker Stadium | |
| 19:45 |  Sandbach United v New Mills | Sandbach Community Football Centre | |
| 19:45 | Shawbury United v Market Drayton Town | Shawbury Utd Community Sports and Recreational Centre | |
| 19:45 | Stockport Georgians v Cheadle Heath Nomads | Cromley Road | |
| 19:45 | Wolverhampton Casuals v Allscott Heath | Brinsford Stadium | |
| 20:00 | Stafford Town v Wolverhampton Sporting Community | Evans Park | |
| Wednesday 30th July 2025 | Premier Division | ||
| 19:45 | Litherland REMYCA v City of Liverpool | Litherland Sports Park | |
| Wednesday 30th July 2025 | First Division South | ||
| 19:45 | Barnton v Cammell Laird 1907 | The Creative Hut Stadium | |
| 19:45 | Eccleshall v Foley Meir | Stoke Signage Stadium | |
| 19:45 | Telford Town v Haughmond | DRM Aggregate Arena | |
| Saturday 2nd August 2025 | The Emirates F.A Cup Prelim Rnd | ||
| 15:00 | Abbey Hey v AFC Liverpool | The Abbey Stadium | |
| 15:00 | Atherton LR v Ossett United  | Crilly Park | |
| 15:00 |  Bury v South Liverpool | Gigg Lane | |
| 15:00 | Chadderton v Stockport Town | Emplas Commercial North Stadium | |
| 15:00 | Charnock Richard v Burscough | Mossie Park | |
| 15:00 | City of Liverpool v Euxton Villa | The Community Ground | |
| 15:00 | Glossop North End v FC St Helens | The Asgard Engineering Stadium | |
| 15:00 |  Golcar United v Ramsbottom United | Skye Direct Stadium | |
| 15:00 | Irlam v Thackley  | The Silver St Stadium | |
| 15:00 |  Liversedge v Wythenshawe | Clayborn Ground | |
| 15:00 |  Penistone Church v Padiham | Church View Road | |
| 15:00 | Pilkington v Longridge Town | PSD Stadium | |
| 15:00 |  Trafford v Barnoldswick Town | Shawe View | |
| 15:00 |  Whitchurch Alport v Litherland REMYCA | KMJ Mortgages Stadium | |
| 15:00 |  Winsford United v West Didsbury & Chorlton | Barton Stadium | |
| 15:00 |  Witton Albion v Cheadle Town | Wincham Park | |
| 15:00 |  Wythenshawe Town v Prestwich Heys | Ericstan Park | |
| Saturday 2nd August 2025 | First Division North | ||
| 15:00 | Colne v Maine Road | Haffners Eats Stadium | |
| 15:00 | Daisy Hill v Garstang | The Ginge Power Stadium | |
| 15:00 | Darwen FC v MSB Woolton  | Multevo Group Anchor Ground | |
| 15:00 | Fulwood Amateurs v Holker Old Boys | Lightfoot Green Lane | |
| 15:00 | Maghull v Droylsden | DT Hughes Community Stadium | |
| 15:00 | Nelson v AFC Blackpool | The Daisy Arena Little Wembley | |
| 15:00 | Squires Gate v Thornton Cleveleys | The Skiddle Community Stadium | |
| Saturday 2nd August 2025 | First Division South | ||
| 15:00 | Allscott Heath v Barnton | The Giant Stadium | |
| 15:00 | Alsager Town v Telford Town | Wood Park | |
| 15:00 | Cammell Laird 1907 v Stafford Town | KRCT LTD STADIUM | |
| 15:00 | Cheadle Heath Nomads v Foley Meir | Ideal Building Systems Stadium | |
| 15:00 | Haughmond v Runcorn Town | Sundorne Sports Village | |
| 15:00 | Market Drayton Town v Stockport Georgians | Greenfields Sports Ground | |
| 15:00 | New Mills v Wolverhampton Casuals | Church Lane | |
| 15:00 | Sandbach United v Shawbury United | Sandbach Community Football Centre | |
| 15:00 | Wolverhampton Sporting Community v Ashville | Pride Park | |
| Tuesday 5th August 2025 | First Division North | ||
| 19:45 | Steeton v Ashton Town | Marley Stadium | |
| Friday 8th August 2025 | Premier Division | ||
| 19:45 | Prestwich Heys v Burscough | Adie Moran Park | |
| Saturday 9th August 2025 | Premier Division | ||
| 15:00 | Chadderton v South Liverpool | Emplas Commercial North Stadium | |
| 15:00 | Charnock Richard v Irlam | Mossie Park | |
| 15:00 | Cheadle Town v AFC Liverpool | The Ground Up Solutions Stadium | |
| 15:00 | City of Liverpool v Atherton LR | The Community Ground | |
| 15:00 | Litherland REMYCA v Barnoldswick Town | Litherland Sports Park | |
| 15:00 | Longridge Town v Wythenshawe | Inglewhite Road | |
| 15:00 | Pilkington v Abbey Hey | PSD Stadium | |
| 15:00 | Ramsbottom United v FC St Helens | Harry Williams Riverside Stadium | |
| 15:00 | Stockport Town v Padiham | Stockport Sports Village | |
| 15:00 | West Didsbury & Chorlton v Euxton Villa | Step Places Stadium | |
| 18:00 | FC Isle of Man v Glossop North End | The Bowl | |
| Saturday 9th August 2025 | First Division North | ||
| 15:00 | AFC Blackpool v Maghull | Mechanics Ground | |
| 15:00 | Ashton Town v Daisy Hill | The Bartons Group Stadium | |
| 15:00 | Colne v Fulwood Amateurs | Haffners Eats Stadium | |
| 15:00 | Garstang v Droylsden | The Riverside | |
| 15:00 | Holker Old Boys v Steeton | The Handmark Engineering Stadium | |
| 15:00 | Maine Road v MSB Woolton | Brantingham Road | |
| 15:00 | Squires Gate v Darwen FC | The Skiddle Community Stadium | |
| 15:00 | Thornton Cleveleys v Ashton Athletic | Gamble Road | |
| Saturday 9th August 2025 | First Division South | ||
| 15:00 | Ashville v Stockport Georgians | Ray Parker Stadium | |
| 15:00 | Cheadle Heath Nomads v Cammell Laird 1907 | Ideal Building Systems Stadium | |
| 15:00 | Eccleshall v Allscott Heath | Stoke Signage Stadium | |
| 15:00 | Foley Meir v Market Drayton Town | Trentham Foods Stadium | |
| 15:00 | Haughmond v New Mills | Sundorne Sports Village | |
| 15:00 | Runcorn Town v Wolverhampton Sporting Community | Viridor Community Stadium | |
| 15:00 | Stafford Town v Barnton | Evans Park | |
| 15:00 | Telford Town v Sandbach United | DRM Aggregate Arena | |
| 15:00 | Wolverhampton Casuals v Alsager Town | Brinsford Stadium | |
| Monday 11th August 2025 | Premier Division | ||
| 19:45 | Stockport Town v Prestwich Heys | Stockport Sports Village | |
| Tuesday 12th August 2025 | Premier Division | ||
| 19:45 | Abbey Hey v Ramsbottom United | The Abbey Stadium | |
| 19:45 | AFC Liverpool v FC St Helens | Berry Street Garage Stadium | |
| 19:45 | Barnoldswick Town v Chadderton | Silentnight Stadium | |
| 19:45 | Burscough v Longridge Town | The Community Ground | |
| 19:45 | Charnock Richard v Pilkington | Mossie Park | |
| 19:45 | Cheadle Town v City of Liverpool | The Ground Up Solutions Stadium | |
| 19:45 | Glossop North End v Wythenshawe | The Asgard Engineering Stadium | |
| 19:45 | Irlam v FC Isle of Man | The Silver St Stadium | |
| 19:45 | Padiham v Euxton Villa | Ruby Civil Arena | |
| Wednesday 13th August 2025 | Premier Division | ||
| 19:45 | South Liverpool v Litherland REMYCA | Jericho Lane | |
| 19:45 | West Didsbury & Chorlton v Atherton LR | Step Places Stadium | |
| Saturday 26th July 2025 Premier Division |
| AFC Liverpool v Irlam (15:00) |
| Burscough v Abbey Hey (15:00) |
| Chadderton v Charnock Richard (15:00) |
| Cheadle Town v Barnoldswick Town (15:00) |
| Euxton Villa v Prestwich Heys (15:00) |
| Glossop North End v City of Liverpool (15:00) |
| Longridge Town v FC St Helens (15:00) |
| Padiham v Wythenshawe (15:00) |
| Ramsbottom United v Atherton LR (15:00) |
| South Liverpool v Stockport Town (15:00) |
| West Didsbury & Chorlton v Pilkington (15:00) |
| FC Isle of Man v Litherland REMYCA (18:00) |
| Saturday 26th July 2025 First Division North |
| Colne v Ashton Town (15:00) |
| Daisy Hill v Ashton Athletic (15:00) |
| Darwen FC v Thornton Cleveleys (15:00) |
| Droylsden v AFC Blackpool (15:00) |
| Holker Old Boys v Nelson (15:00) |
| Maghull v Squires Gate (15:00) |
| Maine Road v Garstang (15:00) |
| Steeton v Fulwood Amateurs (15:00) |
| Saturday 26th July 2025 First Division South |
| Allscott Heath v Cheadle Heath Nomads (15:00) |
| Ashville v Wolverhampton Casuals (15:00) |
| Barnton v Haughmond (15:00) |
| Foley Meir v Telford Town (15:00) |
| New Mills v Alsager Town (15:00) |
| Runcorn Town v Market Drayton Town (15:00) |
| Shawbury United v Cammell Laird 1907 (15:00) |
| Stafford Town v Eccleshall (15:00) |
| Wolverhampton Sporting Community v Stockport Georgians (15:00) |
| Tuesday 29th July 2025 Premier Division |
| Abbey Hey v Stockport Town (19:45) |
| Atherton LR v South Liverpool (19:45) |
| Barnoldswick Town v Charnock Richard (19:45) |
| Burscough v AFC Liverpool (19:45) |
| Cheadle Town v Ramsbottom United (19:45) |
| FC St Helens v FC Isle of Man (19:45) |
| Glossop North End v West Didsbury & Chorlton (19:45) |
| Irlam v Pilkington (19:45) |
| Prestwich Heys v Padiham (19:45) |
| Wythenshawe v Chadderton (19:45) |
| Euxton Villa v Longridge Town (20:00) |
| Tuesday 29th July 2025 First Division South |
| Ashville v Runcorn Town (19:45) |
| Sandbach United v New Mills (19:45) |
| Shawbury United v Market Drayton Town (19:45) |
| Stockport Georgians v Cheadle Heath Nomads (19:45) |
| Wolverhampton Casuals v Allscott Heath (19:45) |
| Stafford Town v Wolverhampton Sporting Community (20:00) |
| Wednesday 30th July 2025 Premier Division |
| Litherland REMYCA v City of Liverpool (19:45) |
| Wednesday 30th July 2025 First Division South |
| Barnton v Cammell Laird 1907 (19:45) |
| Eccleshall v Foley Meir (19:45) |
| Telford Town v Haughmond (19:45) |
| Saturday 2nd August 2025 The Emirates F.A Cup Preliminary Round |
| Abbey Hey v AFC Liverpool (15:00) |
| Atherton LR v Ossett United (15:00) |
| Bury v South Liverpool (15:00) |
| Chadderton v Stockport Town (15:00) |
| Charnock Richard v Burscough (15:00) |
| City of Liverpool v Euxton Villa (15:00) |
| Glossop North End v FC St Helens (15:00) |
| Golcar United v Ramsbottom United (15:00) |
| Irlam v Thackley (15:00) |
| Liversedge v Wythenshawe (15:00) |
| Penistone Church v Padiham (15:00) |
| Pilkington v Longridge Town (15:00) |
| Trafford v Barnoldswick Town (15:00) |
| Whitchurch Alport v Litherland REMYCA (15:00) |
| Winsford United v West Didsbury & Chorlton (15:00) |
| Witton Albion v Cheadle Town (15:00) |
| Wythenshawe Town v Prestwich Heys (15:00) |
| Saturday 2nd August 2025 First Division North |
| Colne v Maine Road (15:00) |
| Daisy Hill v Garstang (15:00) |
| Darwen FC v MSB Woolton (15:00) |
| Fulwood Amateurs v Holker Old Boys (15:00) |
| Maghull v Droylsden (15:00) |
| Nelson v AFC Blackpool (15:00) |
| Squires Gate v Thornton Cleveleys (15:00) |
| Saturday 2nd August 2025 First Division South |
| Allscott Heath v Barnton (15:00) |
| Alsager Town v Telford Town (15:00) |
| Cammell Laird 1907 v Stafford Town (15:00) |
| Cheadle Heath Nomads v Foley Meir (15:00) |
| Haughmond v Runcorn Town (15:00) |
| Market Drayton Town v Stockport Georgians (15:00) |
| New Mills v Wolverhampton Casuals (15:00) |
| Sandbach United v Shawbury United (15:00) |
| Wolverhampton Sporting Community v Ashville (15:00) |
| Tuesday 5th August 2025 First Division North |
| Steeton v Ashton Town (19:45) |
| Friday 8th August 2025 Premier Division |
| Prestwich Heys v Burscough (19:45) |
| Saturday 9th August 2025 Premier Division |
| Chadderton v South Liverpool (15:00) |
| Charnock Richard v Irlam (15:00) |
| Cheadle Town v AFC Liverpool (15:00) |
| City of Liverpool v Atherton LR (15:00) |
| Litherland REMYCA v Barnoldswick Town (15:00) |
| Longridge Town v Wythenshawe (15:00) |
| Pilkington v Abbey Hey (15:00) |
| Ramsbottom United v FC St Helens (15:00) |
| Stockport Town v Padiham (15:00) |
| West Didsbury & Chorlton v Euxton Villa (15:00) |
| FC Isle of Man v Glossop North End (18:00) |
| Saturday 9th August 2025 First Division North |
| AFC Blackpool v Maghull (15:00) |
| Ashton Town v Daisy Hill (15:00) |
| Colne v Fulwood Amateurs (15:00) |
| Garstang v Droylsden (15:00) |
| Holker Old Boys v Steeton (15:00) |
| Maine Road v MSB Woolton (15:00) |
| Squires Gate v Darwen FC (15:00) |
| Thornton Cleveleys v Ashton Athletic (15:00) |
| Saturday 9th August 2025 First Division South |
| Ashville v Stockport Georgians (15:00) |
| Cheadle Heath Nomads v Cammell Laird 1907 (15:00) |
| Eccleshall v Allscott Heath (15:00) |
| Foley Meir v Market Drayton Town (15:00) |
| Haughmond v New Mills (15:00) |
| Runcorn Town v Wolverhampton Sporting Community (15:00) |
| Stafford Town v Barnton (15:00) |
| Telford Town v Sandbach United (15:00) |
| Wolverhampton Casuals v Alsager Town (15:00) |
| Monday 11th August 2025 Premier Division |
| Stockport Town v Prestwich Heys (19:45) |
| Tuesday 12th August 2025 Premier Division |
| Abbey Hey v Ramsbottom United (19:45) |
| AFC Liverpool v FC St Helens (19:45) |
| Barnoldswick Town v Chadderton (19:45) |
| Burscough v Longridge Town (19:45) |
| Charnock Richard v Pilkington (19:45) |
| Cheadle Town v City of Liverpool (19:45) |
| Glossop North End v Wythenshawe (19:45) |
| Irlam v FC Isle of Man (19:45) |
| Padiham v Euxton Villa (19:45) |
| Wednesday 13th August 2025 Premier Division |
| South Liverpool v Litherland REMYCA (19:45) |
| West Didsbury & Chorlton v Atherton LR (19:45) |
