Saturday 7th August 2010
First Division
Norton United	0-0	Holker Old Boys	Att: 0

 

Tuesday 10th August 2010
First Division
Holker Old Boys	4-0	Darwen FC	Att: 0

 

Saturday 14th August 2010
F.A. Challenge Cup Extra Preliminary Round
Holker Old Boys	1-1	Abbey Hey	Att: 1

 

Tuesday 17th August 2010
F.A. Challenge Cup Extra Preliminary Round Replay
Abbey Hey	0-1	Holker Old Boys	Att: 1

 

Saturday 21st August 2010
First Division
Cheadle Town	1-0	Holker Old Boys	Att: 0

 

Saturday 28th August 2010
F.A. Challenge Cup Preliminary Round
Holker Old Boys	0-2	Trafford xx	Att: 2

 

Saturday 4th September 2010
F.A. Carlsberg Vase 1st Qualifying Round
Chadderton	1-2	Holker Old Boys	Att: 2

 

Saturday 11th September 2010
First Division
Runcorn Town	2-3	Holker Old Boys	Att: 3

 

Saturday 18th September 2010
F.A. Carlsberg Vase 2nd Qualifying Round
Holker Old Boys	0-2	Colne	Att: 2

 

Saturday 25th September 2010
First Division
Holker Old Boys	1-3	Atherton Collieries	Att: 3

 

Tuesday 28th September 2010
Lancashire Challenge Trophy 1st Round
Ramsbottom United	3-3	Holker Old Boys	Att: 3

 

Saturday 9th October 2010
First Division
Wigan Robin Park	2-0	Holker Old Boys	Att: 0

 

Saturday 16th October 2010
First Division
Holker Old Boys	2-2	Abbey Hey	Att: 2

 

Saturday 23rd October 2010
First Division
Eccleshall	4-2	Holker Old Boys	Att: 2

 

Tuesday 26th October 2010
First Division
Darwen FC	0-3	Holker Old Boys	Att: 3

 

Saturday 30th October 2010
First Division
Holker Old Boys	8-0	Rochdale Town	Att: 0

 

Saturday 6th November 2010
League Challenge Cup 1st Round
Norton United	3-0	Holker Old Boys	Att: 0

 

Saturday 13th November 2010
First Division
Chadderton	1-0	Holker Old Boys	Att: 0

 

Saturday 20th November 2010
First Division
Holker Old Boys	2-2	Norton United	Att: 2

 

Saturday 11th December 2010
First Division
Ashton Town	1-2	Holker Old Boys	Att: 2

 

Monday 3rd January 2011
First Division
Holker Old Boys	3-2	Ashton Town	Att: 2

 

Saturday 22nd January 2011
First Division Trophy 2nd Round
AFC Blackpool	4-0	Holker Old Boys	Att: 0

 

Saturday 12th February 2011
First Division
Holker Old Boys	1-2	Chadderton	Att: 2

 

Tuesday 15th February 2011
First Division
AFC Blackpool	1-1	Holker Old Boys	Att: 1

 

Tuesday 1st March 2011
First Division
Abbey Hey	0-4	Holker Old Boys	Att: 4

 

Saturday 5th March 2011
First Division
Holker Old Boys	1-1	Oldham Boro	Att: 1

 

Tuesday 8th March 2011
First Division
Holker Old Boys	6-1	Daisy Hill	Att: 1

 

Saturday 12th March 2011
First Division
Holker Old Boys	2-1	Cheadle Town	Att: 1

 

Saturday 19th March 2011
First Division
Holker Old Boys	2-2	Runcorn Town	Att: 2

 

Saturday 26th March 2011
First Division
Holker Old Boys	2-1	Irlam	Att: 1

 

Tuesday 29th March 2011
First Division
Daisy Hill	2-3	Holker Old Boys	Att: 3

 

Saturday 2nd April 2011
First Division
AFC Liverpool	0-1	Holker Old Boys	Att: 1

 

Tuesday 5th April 2011
First Division
Oldham Boro	0-3	Holker Old Boys	Att: 3

 

Saturday 9th April 2011
First Division
Atherton Collieries	2-3	Holker Old Boys	Att: 3

 

Thursday 14th April 2011
First Division
Irlam	3-2	Holker Old Boys	Att: 2

 

Saturday 16th April 2011
First Division
Holker Old Boys	3-0	Leek CSOB	Att: 0

 

Tuesday 19th April 2011
First Division
Holker Old Boys	1-2	AFC Liverpool	Att: 2

 

Saturday 23rd April 2011
First Division
Rochdale Town	0-3	Holker Old Boys	Att: 3

 

Monday 25th April 2011
First Division
Holker Old Boys	2-1	Wigan Robin Park	Att: 1

 

Wednesday 27th April 2011
First Division
Holker Old Boys	1-2	AFC Blackpool	Att: 2

 

Saturday 30th April 2011
First Division
Leek CSOB	1-3	Holker Old Boys	Att: 3

 

Monday 2nd May 2011
First Division
Holker Old Boys	3-0	Eccleshall	Att: 0