| Saturday 13th August 2005 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 9-0 | Stone Dominoes | Att: 0 |
| Tuesday 16th August 2005 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 4-1 | Nantwich Town | Att: 1 |
| Saturday 20th August 2005 | F.A. Challenge Cup Extra Preliminary Round | ||
|---|---|---|---|
| Skelmersdale United | 1-0 | Liversedge | Att: 132 |
| Tuesday 23rd August 2005 | First Division | ||
|---|---|---|---|
| St Helens Town | 2-5 | Skelmersdale United | Att: 5 |
| Saturday 27th August 2005 | F.A. Challenge Cup Preliminary Round | ||
|---|---|---|---|
| Skelmersdale United | 2-0 | Colwyn Bay | Att: 219 |
| Tuesday 30th August 2005 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 2-1 | Cammell Laird | Att: 1 |
| Saturday 3rd September 2005 | First Division | ||
|---|---|---|---|
| Atherton Collieries | 0-8 | Skelmersdale United | Att: 8 |
| Tuesday 6th September 2005 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 6-1 | Alsager Town | Att: 1 |
| Saturday 10th September 2005 | F.A. Challenge Cup 1st Qualifying Round | ||
|---|---|---|---|
| Runcorn FC Halton | 2-3 | Skelmersdale United | Att: 129 |
| Thursday 15th September 2005 | First Division | ||
|---|---|---|---|
| Bacup Borough | 0-4 | Skelmersdale United | Att: 4 |
| Saturday 17th September 2005 | First Division | ||
|---|---|---|---|
| Maine Road | 0-1 | Skelmersdale United | Att: 1 |
| Tuesday 20th September 2005 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 2-1 | Ramsbottom United | Att: 1 |
| Saturday 24th September 2005 | F.A. Challenge Cup 2nd Qualifying Round | ||
|---|---|---|---|
| Skelmersdale United | 0-0 | Bishop Auckland | Att: 509 |
| Tuesday 27th September 2005 | F.A. Challenge Cup 2nd Qualifying Round Replay | ||
|---|---|---|---|
| Bishop Auckland | 1-2 | Skelmersdale United | Att: 125 |
| Saturday 1st October 2005 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 2-0 | Colne | Att: 0 |
| Saturday 8th October 2005 | F.A. Challenge Cup 3rd Qualifying Round | ||
|---|---|---|---|
| Vauxhall | 4-3 | Skelmersdale United | Att: 243 |
| Saturday 15th October 2005 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 6-2 | Atherton LR | Att: 2 |
| Tuesday 18th October 2005 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 2-1 | Curzon Ashton | Att: 1 |
| Saturday 22nd October 2005 | First Division | ||
|---|---|---|---|
| Salford City | 2-2 | Skelmersdale United | Att: 2 |
| Saturday 29th October 2005 | First Division | ||
|---|---|---|---|
| Colne | 4-1 | Skelmersdale United | Att: 1 |
| Saturday 19th November 2005 | F.A. Carlsberg Vase 2nd Round | ||
|---|---|---|---|
| Skelmersdale United | 4-3 | West Allotment Celtic | Att: 141 |
| Saturday 26th November 2005 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 2-0 | Bacup Borough | Att: 0 |
| Saturday 3rd December 2005 | First Division | ||
|---|---|---|---|
| Curzon Ashton | 1-0 | Skelmersdale United | Att: 0 |
| Saturday 10th December 2005 | F.A. Carlsberg Vase 3rd Round | ||
|---|---|---|---|
| Squires Gate | 2-1 | Skelmersdale United | Att: 102 |
| Tuesday 13th December 2005 | First Division | ||
|---|---|---|---|
| Trafford | 1-2 | Skelmersdale United | Att: 2 |
| Saturday 17th December 2005 | First Division | ||
|---|---|---|---|
| Congleton Town | 1-1 | Skelmersdale United | Att: 1 |
| Tuesday 20th December 2005 | First Division | ||
|---|---|---|---|
| Cammell Laird | 1-1 | Skelmersdale United | Att: 1 |
| Monday 26th December 2005 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 4-0 | Squires Gate | Att: 0 |
| Monday 2nd January 2006 | First Division | ||
|---|---|---|---|
| Atherton LR | 1-0 | Skelmersdale United | Att: 0 |
| Saturday 7th January 2006 | First Division | ||
|---|---|---|---|
| Formby | 0-5 | Skelmersdale United | Att: 5 |
| Saturday 14th January 2006 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 0-2 | Glossop North End | Att: 2 |
| Saturday 21st January 2006 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 6-1 | St Helens Town | Att: 1 |
| Saturday 28th January 2006 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 5-3 | Trafford | Att: 3 |
| Tuesday 31st January 2006 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 1-1 | Atherton Collieries | Att: 1 |
| Saturday 4th February 2006 | First Division | ||
|---|---|---|---|
| Abbey Hey | 3-1 | Skelmersdale United | Att: 1 |
| Saturday 11th February 2006 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 5-1 | Newcastle Town | Att: 1 |
| Saturday 25th February 2006 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 4-1 | Silsden | Att: 1 |
| Saturday 11th March 2006 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 2-1 | Salford City | Att: 1 |
| Tuesday 14th March 2006 | First Division | ||
|---|---|---|---|
| Nantwich Town | 1-2 | Skelmersdale United | Att: 2 |
| Saturday 18th March 2006 | First Division | ||
|---|---|---|---|
| Alsager Town | 1-1 | Skelmersdale United | Att: 1 |
| Wednesday 22nd March 2006 | First Division | ||
|---|---|---|---|
| Silsden | 1-5 | Skelmersdale United | Att: 5 |
| Saturday 25th March 2006 | First Division | ||
|---|---|---|---|
| Stone Dominoes | 2-4 | Skelmersdale United | Att: 4 |
| Saturday 1st April 2006 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 3-1 | Maine Road | Att: 1 |
| Tuesday 4th April 2006 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 1-1 | Formby | Att: 1 |
| Saturday 8th April 2006 | First Division | ||
|---|---|---|---|
| Ramsbottom United | 2-0 | Skelmersdale United | Att: 0 |
| Monday 17th April 2006 | First Division | ||
|---|---|---|---|
| Squires Gate | 0-1 | Skelmersdale United | Att: 1 |
| Saturday 22nd April 2006 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 3-3 | Abbey Hey | Att: 3 |
| Saturday 29th April 2006 | First Division | ||
|---|---|---|---|
| Newcastle Town | 1-2 | Skelmersdale United | Att: 2 |
| Tuesday 2nd May 2006 | First Division | ||
|---|---|---|---|
| Skelmersdale United | 3-0 | Congleton Town | Att: 0 |
| Friday 12th May 2006 | First Division | ||
|---|---|---|---|
| Glossop North End | 2-1 | Skelmersdale United | Att: 1 |
