| Sat 20/08/22 | Lower Breck v Irlam | 0-2 | | | | |  |
| Tue 23/08/22 | Northwich Victoria v Lower Breck | 2-0 | | | | | |
| Sat 27/08/22 | Lower Breck v Daisy Hill | 3-3 | | | | | |
| Mon 29/08/22 | Lower Breck v Wythenshawe Town | - | | | | | |
| Sat 03/09/22 | Winsford United v Lower Breck | 2-3 | | | | | |
| Thu 08/09/22 | Lower Breck v Bury AFC | 2-0 | | | | | |
| Wed 14/09/22 | Litherland REMYCA v Lower Breck | 1-0 | | | | | |
| Sat 17/09/22 | Lower Breck v Kendal Town | 1-0 | | | | | |
| Sat 24/09/22 | FC Isle of Man v Lower Breck | 3-1 | | | | | |
| Thu 29/09/22 | Lower Breck v Ashton Athletic | 0-1 | | | | | |
| Tue 04/10/22 | West Didsbury & Chorlton v Lower Breck | 1-4 | | | | | |
| Sat 08/10/22 | Lower Breck v Northwich Victoria | 1-3 | | | | | |
| Sat 15/10/22 | Litherland REMYCA v Lower Breck | 0-4 | | | | | |
| Thu 20/10/22 | Lower Breck v AFC Liverpool | 2-0 | | | | | |
| Sat 22/10/22 | Congleton Town v Lower Breck | 2-1 | | | | | |
| Sat 29/10/22 | Lower Breck v Barnoldswick Town | 1-0 | | | | | |
| Thu 03/11/22 | Lower Breck v Wythenshawe Town | 4-0 | | | | | |
| Sat 05/11/22 | Burscough v Lower Breck | 0-0 | | | | | |
| Sat 12/11/22 | Lower Breck v Winsford United | 1-2 | | | | | |
| Wed 16/11/22 | AFC Liverpool v Lower Breck | 0-0 | | | | | |
| Sat 19/11/22 | Lower Breck v Wythenshawe Amateurs | 4-0 | | | | | |
| Sat 26/11/22 | Bury AFC v Lower Breck | 3-1 | | | | | |
| Wed 30/11/22 | AFC Liverpool v Lower Breck | 4-3 | | | | | |
| Mon 26/12/22 | Prestwich Heys v Lower Breck | 1-0 | | | | | |
| Fri 06/01/23 | Lower Breck v Avro | 2-2 | | | | | |
| Thu 12/01/23 | Lower Breck v Padiham | 3-3 | | |  | | |
| Sat 14/01/23 | Lower Breck v Squires Gate | 3-1 | | | | | |
| Tue 24/01/23 | Charnock Richard v Lower Breck | 2-1 | | | | | |
| Thu 26/01/23 | Lower Breck v Congleton Town | 0-1 | | | | | |
| Sat 28/01/23 | Barnoldswick Town v Lower Breck | 3-3 | | | | | |
| Sat 04/02/23 | Lower Breck v Longridge Town | 2-3 | | | | | |
| Sat 11/02/23 | Kendal Town v Lower Breck | 1-1 | | | | | |
| Sat 25/02/23 | Ashton Athletic v Lower Breck | 0-1 | | | | | |
| Sat 04/03/23 | Vauxhall Motors v Lower Breck | 6-1 | | | | | |
| Sat 11/03/23 | Lower Breck v Charnock Richard | 3-0 | | | | | |
| Thu 16/03/23 | Lower Breck v Congleton Town | 1-2 | | | | | |
| Sat 18/03/23 | Irlam v Lower Breck | 0-0 | | | | | |
| Sat 25/03/23 | Wythenshawe Town v Lower Breck | 2-0 | | | | | |
| Sat 01/04/23 | Lower Breck v FC Isle of Man | 0-2 | | | | | |
| Mon 10/04/23 | Lower Breck v Prestwich Heys | 3-1 | | | | | |
| Thu 13/04/23 | Lower Breck v West Didsbury & Chorlton | 1-1 | | | | | |
| Sat 15/04/23 | Squires Gate v Lower Breck | 1-2 | | | | | |
| Sat 22/04/23 | Lower Breck v Litherland REMYCA | 0-1 | | | | | |
