| Sat 04/09/21 | Abbey Hulton United v Maine Road * | 3-2 | | | | | |
| Tue 07/09/21 | Stafford Town v Abbey Hulton United | 2-0 | | | | | |
| Sat 11/09/21 | Atherstone Town v Abbey Hulton United | 2-1 | | |  | | |
| Sat 18/09/21 | Abbey Hulton United v Cheadle Heath Nomads | 3-1 | | | | |  |
| Sat 25/09/21 | Stockport Town v Abbey Hulton United | 3-2 | | | | | |
| Sat 16/10/21 | Abbey Hulton United v FC Isle of Man | 3-8 | | | | | |
| Sat 23/10/21 | Eccleshall v Abbey Hulton United | 0-1 | | | | | |
| Sat 30/10/21 | Ellesmere Rangers v Abbey Hulton United | 4-2 | | | | | |
| Sat 06/11/21 | Alsager Town v Abbey Hulton United | 1-0 | | | | | |
| Wed 10/11/21 | Abbey Hulton United v Stoke City | 1-4 | | | | | |
| Sat 13/11/21 | Wythenshawe Amateurs v Abbey Hulton United | 2-1 | | | | | |
| Sat 20/11/21 | Abbey Hulton United v Brocton | 4-1 | | | | | |
| Sat 27/11/21 | Cheadle Town v Abbey Hulton United | 3-3 | | | | | |
| Sat 04/12/21 | Abbey Hulton United v Stockport Town | 1-2 | | | | | |
| Sat 18/12/21 | Abbey Hulton United v St Martins | 6-0 | | | | | |
| Mon 27/12/21 | Abbey Hulton United v New Mills | 0-1 | | | | | |
| Sat 22/01/22 | West Didsbury & Chorlton v Abbey Hulton United | 4-1 | | | | | |
| Sat 29/01/22 | Abbey Hulton United v Alsager Town | 4-1 | | | | | |
| Sat 05/02/22 | Abbey Hulton United v Eccleshall | 1-3 | | | | | |
| Sat 12/02/22 | Abbey Hulton United v Stafford Town | - | | | | | |
| Sat 26/02/22 | Abbey Hulton United v Ellesmere Rangers | 1-0 | | | | | |
| Tue 01/03/22 | Abbey Hulton United v Stafford Town | 0-0 | | | | | |
| Sat 05/03/22 | Rocester v Abbey Hulton United | 2-4 | | | | | |
| Sat 12/03/22 | Abbey Hulton United v Wythenshawe Amateurs | 0-1 | | | | | |
| Tue 15/03/22 | Abbey Hulton United v Alsager Town | 1-3 | | | | | |
| Sat 19/03/22 | Abbey Hey v Abbey Hulton United | 2-1 | | | | | |
| Tue 22/03/22 | Cheadle Heath Nomads v Abbey Hulton United | 0-4 | | | | | |
| Sat 26/03/22 | Sandbach United v Abbey Hulton United | 6-0 | | | | | |
| Mon 28/03/22 | Maine Road v Abbey Hulton United | 4-0 | | | | | |
| Sat 02/04/22 | FC Isle of Man v Abbey Hulton United | 2-1 | | | | | |
| Tue 05/04/22 | Abbey Hulton United v Rocester | 1-0 |  | | | | |
| Sat 23/04/22 | Ilkley Town v Abbey Hulton United | 2-0 | | | | | |
