| Sat 01/11/25 | Charnock Richard v Litherland REMYCA * | 3-0 | | | | | | |
| Sat 22/11/25 | Litherland REMYCA v Stockport Town | 0-6 | | | | | | |
| Wed 26/11/25 | Litherland REMYCA v Prestwich Heys | 0-2 | | | |  | | |
| Fri 28/11/25 | FC St Helens v Litherland REMYCA | 1-0 | | | | | | |
| Wed 03/12/25 | Litherland REMYCA v Cheadle Town | 4-2 | | | | | | |
| Sat 06/12/25 | Glossop North End v Litherland REMYCA | 4-1 | | | | | | |
| Wed 10/12/25 | Litherland REMYCA v South Liverpool (CUP) | 1-4 | | | | | | |
| Sat 13/12/25 | Litherland REMYCA v Longridge Town * | 0-2 | | | | | | |
| Sat 20/12/25 | Abbey Hey v Litherland REMYCA | 6-2 | | | | | | |
| Sat 27/12/25 | Litherland REMYCA v AFC Liverpool | 1-3 | | | | | | |
| Sat 24/01/26 | Irlam v Litherland REMYCA | 4-0 | | | | | | |
| Wed 28/01/26 | Litherland REMYCA v FC St Helens | 2-2 | | | | | | |
| Sat 31/01/26 | Barnoldswick Town v Litherland REMYCA | 2-2 | | | | | | |
| Sat 14/02/26 | Chadderton v Litherland REMYCA | 2-0 | | | | | | |
| Sat 28/02/26 | Litherland REMYCA v Pilkington | 4-1 | | | | | | |
| Tue 03/03/26 | Ramsbottom United v Litherland REMYCA | 1-1 | | | | | | |
| Sat 07/03/26 | Prestwich Heys v Litherland REMYCA | 2-1 | | | | | | |
| Wed 11/03/26 | Litherland REMYCA v West Didsbury & Chorlton | 1-1 | | | | | | |
| Sat 14/03/26 | Litherland REMYCA v Charnock Richard | 2-5 | | | | | | |
| Sat 21/03/26 | City of Liverpool v Litherland REMYCA | 0-4 | |  | | | | |
| Tue 24/03/26 | Cheadle Town v Litherland REMYCA | 0-3 | | | | | | |
| Sat 28/03/26 | Litherland REMYCA v Abbey Hey | 2-2 | | | | | | |
| Mon 06/04/26 | AFC Liverpool v Litherland REMYCA * | 3-1 | | | | | | |
| Sat 11/04/26 | Litherland REMYCA v Atherton LR * | 0-4 | | | | | | |
