| Sat 30/07/22 | Bury AFC v Litherland REMYCA | 1-0 | | | |  | |
| Wed 03/08/22 | Litherland REMYCA v FC Isle of Man | 1-2 | | | | | |
| Wed 10/08/22 | Litherland REMYCA v Prestwich Heys | 3-4 | | | | | |
| Sat 13/08/22 | Litherland REMYCA v Squires Gate | 0-2 | | | | | |
| Wed 17/08/22 | Litherland REMYCA v Wythenshawe Town * | 1-3 | | | | | |
| Sat 20/08/22 | Litherland REMYCA v Ashton Athletic * | 2-0 | | | | | |
| Tue 23/08/22 | Longridge Town v Litherland REMYCA * | 0-1 | | | | | |
| Sat 27/08/22 | Litherland REMYCA v Staveley Miners Welfare * | 2-0 | | | | | |
| Sat 19/11/22 | Prestwich Heys v Litherland REMYCA | 1-0 | | | | | |
| Tue 22/11/22 | West Didsbury & Chorlton v Litherland REMYCA | 2-1 | | | | | |
| Sat 26/11/22 | Litherland REMYCA v AFC Liverpool | 0-0 | | | | | |
| Sat 03/12/22 | Litherland REMYCA v Avro | 0-1 | | | | | |
| Sat 10/12/22 | FC Isle of Man v Litherland REMYCA | 2-3 | | | | | |
| Sat 07/01/23 | Litherland REMYCA v Burscough | 2-1 | | |  | | |
| Sat 14/01/23 | Litherland REMYCA v Prestwich Heys | 1-0 | | | | | |
| Sat 28/01/23 | Charnock Richard v Litherland REMYCA | 4-5 | | | | | |
| Sat 04/02/23 | Litherland REMYCA v Bury AFC * | 0-1 | | | | | |
| Wed 08/02/23 | Litherland REMYCA v Barnoldswick Town | 2-1 | | | | | |
| Sat 11/02/23 | Burscough v Litherland REMYCA | 2-3 | | | | | |
| Sat 18/02/23 | Wythenshawe Town v Litherland REMYCA | 3-0 | | | | | |
| Sat 25/02/23 | Squires Gate v Litherland REMYCA | 0-2 | | | | | |
| Wed 01/03/23 | Litherland REMYCA v Winsford United | 1-1 | | | | | |
| Sat 04/03/23 | Litherland REMYCA v Longridge Town | 1-1 | | | | | |
| Wed 08/03/23 | Litherland REMYCA v Northwich Victoria | 1-0 | | | | | |
| Sat 11/03/23 | Kendal Town v Litherland REMYCA | 2-2 | | | | | |
| Sat 18/03/23 | Ashton Athletic v Litherland REMYCA | 0-5 | | | | | |
