| Tue 29/10/24 | Prestwich Heys v West Didsbury & Chorlton | 2-2 |  | | |  | |  |
| Sat 02/11/24 | Prestwich Heys v Barnoldswick Town | 0-2 | | | | | | |
| Sat 09/11/24 | Pilkington v Prestwich Heys | 3-2 | | | | | | |
| Sat 16/11/24 | Prestwich Heys v Cheadle Town | 1-4 | | | | | | |
| Fri 22/11/24 | Chadderton v Prestwich Heys | 3-0 | | | | | | |
| Tue 26/11/24 | Prestwich Heys v Cheadle Heath Nomads (CUP) | 1-0 | |  | | | | |
| Sat 30/11/24 | Prestwich Heys v Charnock Richard | 0-4 | | | | | | |
| Fri 13/12/24 | Prestwich Heys v Ramsbottom United (CUP) | 0-5 | | | | | | |
| Sat 21/12/24 | Prestwich Heys v Longridge Town | 2-1 | | | | | | |
| Thu 26/12/24 | Irlam v Prestwich Heys | 1-0 | | | | | | |
| Sat 28/12/24 | Bury v Prestwich Heys | 5-2 | | | | | | |
| Sat 04/01/25 | Prestwich Heys v Squires Gate | 3-0 | | | | | | |
| Thu 16/01/25 | Lower Breck v Prestwich Heys | 2-1 | | | | | | |
| Sat 18/01/25 | Prestwich Heys v South Liverpool | 4-1 | | | | | | |
| Sat 25/01/25 | Prestwich Heys v Litherland REMYCA | 1-0 | | | | | | |
| Sat 01/02/25 | Glossop North End v Prestwich Heys | 2-1 | | | | | | |
| Tue 04/02/25 | West Didsbury & Chorlton v Prestwich Heys | 1-2 | | | | | | |
| Sat 08/02/25 | Prestwich Heys v Bury | 0-2 | | | | | | |
| Sat 15/02/25 | Prestwich Heys v Pilkington | 2-2 | | | | | | |
| Sat 22/02/25 | AFC Liverpool v Prestwich Heys | 3-0 | | | | | | |
| Sun 02/03/25 | Abbey Hey v Prestwich Heys | 0-0 | | | | |  | |
| Sat 08/03/25 | Prestwich Heys v Burscough | 1-2 | | | | | | |
| Sat 05/04/25 | Barnoldswick Town v Prestwich Heys | 2-3 | | | | | | |
| Sat 12/04/25 | Prestwich Heys v Irlam | 2-1 | | | | | | |
| Sat 19/04/25 | Longridge Town v Prestwich Heys | 1-0 | | | | | | |
