| Sat 31/08/24 | Irlam v Pilkington * | 3-1 | | | | | | |
| Sat 07/09/24 | Irlam v Charnock Richard * | 3-2 | | | | | | |
| Tue 10/09/24 | Irlam v Wythenshawe (CUP) | 0-0 | |  | | | | |
| Tue 17/09/24 | Irlam v Barnoldswick Town * | 3-0 | | | | | | |
| Sat 21/09/24 | Squires Gate v Irlam * | 2-3 | | | | | | |
| Thu 26/09/24 | Lower Breck v Irlam * | 2-2 | | | | | | |
| Sat 28/09/24 | Irlam v Cheadle Town * | 1-3 | | | | | | |
| Tue 01/10/24 | Prestwich Heys v Irlam (CUP) | 2-2 | | | | | | |
| Sat 05/10/24 | Pilkington v Irlam | 1-3 | | | | | | |
| Tue 15/10/24 | Irlam v Glossop North End (CUP) | 3-0 | | | | | | |
| Tue 22/10/24 | Irlam v Litherland REMYCA | 5-0 | | | | | | |
| Sat 09/11/24 | Irlam v Lower Breck | 2-2 | | | | | | |
| Tue 12/11/24 | Irlam v West Didsbury & Chorlton * | 3-2 | | | | | | |
| Tue 26/11/24 | Irlam v Ashton United (CUP) | 4-2 | | | | | | |
| Sat 30/11/24 | Irlam v Ramsbottom United | 1-1 | | | | | | |
| Tue 10/12/24 | Irlam v Bury | 1-1 |  | | | |  | |
| Sat 14/12/24 | Irlam v South Liverpool | 5-1 | | | | | |  |
| Thu 26/12/24 | Irlam v Prestwich Heys | 1-0 | | | |  | | |
| Wed 15/01/25 | Litherland REMYCA v Irlam | 1-2 | | | | | | |
| Sat 25/01/25 | Irlam v Glossop North End | 2-1 | | | | | | |
| Mon 27/01/25 | Stockport Town v Irlam * | 1-2 | | | | | | |
| Sat 01/02/25 | FC Isle of Man v Irlam | 1-1 | | | | | | |
| Wed 05/02/25 | Chadderton v Irlam (CUP) | 2-3 | | | | | | |
| Sat 08/02/25 | Padiham v Irlam | 1-2 | | | | | | |
| Sat 15/02/25 | Irlam v AFC Liverpool | 2-1 | | | | | | |
| Sat 22/02/25 | Irlam v Burscough | 1-2 | | | | | | |
| Fri 28/02/25 | Chadderton v Irlam | 0-6 | | | | | | |
| Sat 08/03/25 | Irlam v Colne * | 2-2 | | |  | | | |
| Sat 15/03/25 | Irlam v Longridge Town | 0-0 | | | | | | |
| Sat 22/03/25 | Charnock Richard v Irlam * | 4-0 | | | | | | |
| Sat 29/03/25 | South Liverpool v Irlam | 0-0 | | | | | | |
| Sat 12/04/25 | Prestwich Heys v Irlam * | 2-1 | | | | | | |
| Tue 15/04/25 | Irlam v Hyde United (CUP) | 3-2 | | | | | | |
