| Sat 30/07/22 | Squires Gate v AFC Liverpool * | 1-4 | | | | | |
| Tue 09/08/22 | Burscough v AFC Liverpool * | 1-6 | | | | | |
| Sat 13/08/22 | AFC Liverpool v Northwich Victoria * | 1-3 | | | | | |
| Tue 16/08/22 | Longridge Town v AFC Liverpool * | 0-3 | | | | | |
| Tue 23/08/22 | Ashton Athletic v AFC Liverpool * | 1-2 | | | | | |
| Mon 29/08/22 | AFC Liverpool v FC Isle of Man * | 5-2 | | | | | |
| Sat 03/09/22 | Prestwich Heys v AFC Liverpool * | 0-2 | | | | | |
| Tue 13/09/22 | Charnock Richard v AFC Liverpool * | 3-3 | | | | | |
| Wed 21/09/22 | AFC Liverpool v Litherland REMYCA * | 1-0 | | | | | |
| Sat 24/09/22 | AFC Liverpool v Bury AFC * | 1-0 | | | | | |
| Fri 07/10/22 | AFC Liverpool v Barnoldswick Town | 3-0 | | | | | |
| Sun 16/10/22 | AFC Liverpool v FC Isle of Man | 1-0 | | | | | |
| Sat 22/10/22 | Winsford United v AFC Liverpool * | 1-1 | | | | | |
| Wed 26/10/22 | AFC Liverpool v Padiham * | 2-0 | | | | | |
| Sat 29/10/22 | AFC Liverpool v Avro | 1-0 | | | | | |
| Tue 08/11/22 | Congleton Town v AFC Liverpool | 2-0 | | | | | |
| Wed 16/11/22 | AFC Liverpool v Lower Breck * | 0-0 | | |  | | |
| Sat 19/11/22 | Wythenshawe Town v AFC Liverpool | 5-1 | | | | | |
| Wed 30/11/22 | AFC Liverpool v Lower Breck * | 4-3 | | | | | |
| Sat 03/12/22 | AFC Liverpool v Cheadle Town * | 2-1 | | | | | |
| Sat 17/12/22 | FC Isle of Man v AFC Liverpool | 0-2 | | | | | |
| Mon 26/12/22 | AFC Liverpool v Vauxhall Motors * | 4-2 | | | | | |
| Sat 07/01/23 | AFC Liverpool v West Didsbury & Chorlton * | 5-3 | | | | | |
| Wed 18/01/23 | AFC Liverpool v Kendal Town * | 5-0 | | | | | |
| Wed 01/02/23 | Northwich Victoria v AFC Liverpool * | 2-0 | | | | | |
| Wed 08/02/23 | AFC Liverpool v Longridge Town * | 3-2 | | | | | |
| Sat 18/02/23 | West Didsbury & Chorlton v AFC Liverpool * | 3-0 | | | | | |
