| Fri 07/10/22 | AFC Liverpool v Barnoldswick Town | 3-0 | | | | | |
| Tue 08/11/22 | Barnoldswick Town v West Didsbury & Chorlton * | 2-1 | | | | | |
| Sat 12/11/22 | Barnoldswick Town v Horden Community Welfare | 1-2 |  | | | | |
| Tue 15/11/22 | Wythenshawe Town v Barnoldswick Town * | 2-3 | | | | | |
| Sat 19/11/22 | Barnoldswick Town v Abbey Hey * | 1-1 | | | | | |
| Sat 26/11/22 | Barnoldswick Town v Wakefield AFC | 8-3 | | | | | |
| Wed 30/11/22 | Kendal Town v Barnoldswick Town | 3-1 | | | | | |
| Sat 03/12/22 | Barnoldswick Town v FC Isle of Man | 0-1 | | | | | |
| Tue 06/12/22 | Bury AFC v Barnoldswick Town | 2-0 | | | | | |
| Wed 21/12/22 | Barnoldswick Town v Wythenshawe Town | 3-2 | | | | | |
| Mon 26/12/22 | Padiham v Barnoldswick Town | 1-2 | | | | |  |
| Mon 02/01/23 | Barnoldswick Town v AFC Liverpool | 2-1 | | | | | |
| Tue 24/01/23 | Barnoldswick Town v Golcar United * | 3-1 | | | | | |
| Thu 26/01/23 | Barnoldswick Town v Northwich Victoria | 3-4 | | | | | |
| Sat 28/01/23 | Barnoldswick Town v Lower Breck | 3-3 | | | | | |
| Sat 04/02/23 | Ashton Athletic v Barnoldswick Town | 2-2 | | | | | |
| Wed 08/02/23 | Litherland REMYCA v Barnoldswick Town | 2-1 | | | | | |
| Sat 11/02/23 | Vauxhall Motors v Barnoldswick Town | 2-0 | | | | | |
| Wed 15/02/23 | Barnoldswick Town v Squires Gate | 0-2 | | | | | |
| Sat 04/03/23 | Barnoldswick Town v Burscough | 1-1 | | | | | |
| Sat 18/03/23 | Charnock Richard v Barnoldswick Town | 2-1 | | | | | |
| Thu 23/03/23 | Congleton Town v Barnoldswick Town | 1-0 | | | | | |
| Thu 30/03/23 | Liversedge v Barnoldswick Town | 3-1 | | | | | |
| Sat 01/04/23 | Prestwich Heys v Barnoldswick Town | 2-4 | | | | | |
| Tue 04/04/23 | Barnoldswick Town v Congleton Town | 1-0 | | |  | | |
| Mon 10/04/23 | Barnoldswick Town v Padiham | - | | | | | |
| Wed 12/04/23 | Barnoldswick Town v Longridge Town | 2-4 | | | | | |
| Sat 15/04/23 | Winsford United v Barnoldswick Town | 3-0 | | | | | |
| Tue 18/04/23 | Barnoldswick Town v Bury AFC | 0-2 | | | | | |
| Thu 20/04/23 | Barnoldswick Town v Padiham | 1-1 | | | | | |
| Sat 22/04/23 | Avro v Barnoldswick Town * | 4-0 | | | | | |
