| Sat 30/07/22 | Stafford Town v New Mills | 2-4 | | | | | |
| Tue 02/08/22 | Alsager Town v New Mills | 1-1 | | | | | |
| Sat 06/08/22 | Ossett United v New Mills | 2-0 | | | | | |
| Tue 09/08/22 | New Mills v Wythenshawe Amateurs * | 1-3 | | | | | |
| Sat 13/08/22 | New Mills v Maine Road * | 1-2 | | | | | |
| Tue 16/08/22 | Cammell Laird 1907 v New Mills * | 3-2 | | | | | |
| Sat 20/08/22 | Rocester v New Mills * | 0-5 | | | | | |
| Sat 27/08/22 | New Mills v Atherton LR * | 2-1 |  | | | | |
| Mon 29/08/22 | New Mills v Sandbach United | 4-1 | | | | |  |
| Sat 03/09/22 | New Mills v Eccleshall | 0-2 | | | | | |
| Tue 06/09/22 | Abbey Hulton United v New Mills | 3-0 | | | | | |
| Sat 17/09/22 | New Mills v Stockport Georgians * | 2-2 | | | | | |
| Sat 24/09/22 | New Mills v Brigg Town * | 0-3 | | | | | |
| Sat 01/10/22 | Ashville v New Mills | 1-2 | | | | | |
| Sat 08/10/22 | Wythenshawe Amateurs v New Mills | 0-0 | | | | | |
| Sat 22/10/22 | Foley Meir v New Mills * | 1-2 | | | | | |
| Sat 29/10/22 | New Mills v Foley Meir | 5-2 | | | | | |
| Sat 05/11/22 | Barnton v New Mills | 1-3 | | | | | |
| Tue 08/11/22 | New Mills v Belper United | 1-6 | | | | | |
| Sat 26/11/22 | New Mills v Ashville * | 1-3 | | |  | | |
| Sat 03/12/22 | New Mills v Abbey Hulton United * | 3-0 | | | | | |
| Tue 20/12/22 | New Mills v Brocton * | 3-4 | | | | | |
| Sat 07/01/23 | Brocton v New Mills | 3-0 | | | | | |
| Tue 24/01/23 | New Mills v Stafford Town * | 1-1 | | | | | |
| Sat 28/01/23 | Wythenshawe Amateurs v New Mills * | 3-4 | | | | | |
| Tue 31/01/23 | New Mills v Kendal Town * | 0-3 | | | | | |
| Sat 04/02/23 | New Mills v Cheadle Heath Nomads * | 1-3 | | | | | |
| Sat 11/02/23 | Maine Road v New Mills * | 0-0 | | | | | |
| Tue 14/02/23 | Ellesmere Rangers v New Mills | 3-4 | | | | | |
| Sat 18/02/23 | New Mills v Cheadle Town | 4-2 | | | | | |
| Tue 21/02/23 | Cheadle Heath Nomads v New Mills | 0-0 | | | | | |
| Sat 25/02/23 | Sandbach United v New Mills | 4-2 | | | | | |
| Tue 28/02/23 | New Mills v Alsager Town | 1-1 | | | | | |
| Sat 04/03/23 | Stockport Town v New Mills | 2-2 | | | | | |
| Tue 07/03/23 | Stockport Georgians v New Mills | 0-2 | | | | | |
| Sat 18/03/23 | New Mills v Rocester | 8-0 | | | | | |
| Sat 25/03/23 | Cheadle Town v New Mills | 0-1 | | | | | |
| Tue 28/03/23 | New Mills v Ellesmere Rangers | 4-1 | | | | | |
| Sat 01/04/23 | New Mills v Cammell Laird 1907 | 1-0 | | | | | |
| Mon 10/04/23 | Abbey Hey v New Mills | 2-1 | | | | | |
| Sat 15/04/23 | Eccleshall v New Mills * | 0-1 | | | | | |
