| Sat 06/08/22 | Ashton Town v Nelson * | 1-2 | | |  |  | |
| Tue 09/08/22 | Steeton v Ashton Town | 2-1 | | | | |  |
| Sat 20/08/22 | Ashton Town v Atherton LR | 0-1 | | | | | |
| Sat 27/08/22 | West Didsbury & Chorlton v Ashton Town | 3-1 | | | | | |
| Mon 29/08/22 | Runcorn Town v Ashton Town | 2-0 | | | | | |
| Sat 03/09/22 | Ashton Town v Ilkley Town | 1-4 | | | | | |
| Sat 17/09/22 | Ashton Town v Bacup Borough | 3-3 | | | | | |
| Tue 27/09/22 | AFC Blackpool v Ashton Town | 0-0 | | | | | |
| Sat 01/10/22 | Holker Old Boys v Ashton Town | 6-2 | | | | | |
| Sat 08/10/22 | Ashton Town v Runcorn Town * | 2-0 | | | | | |
| Sat 15/10/22 | Garstang v Ashton Town | 2-1 | | | | | |
| Sat 22/10/22 | Ashton Town v Chadderton | 0-3 | | | | | |
| Wed 26/10/22 | Pilkington v Ashton Town | 4-3 | | | | | |
| Sat 29/10/22 | FC St Helens v Ashton Town | 6-0 | | | | | |
| Sat 12/11/22 | Ashton Town v Steeton * | 1-3 | | | | | |
| Sat 19/11/22 | Ilkley Town v Ashton Town | 1-2 | | | | | |
| Tue 22/11/22 | Euxton Villa v Ashton Town | 2-0 | | | | | |
| Sat 26/11/22 | Pilkington v Ashton Town | 4-2 | | | | | |
| Fri 02/12/22 | South Liverpool v Ashton Town * | 2-1 | | | | | |
| Mon 23/01/23 | Daisy Hill v Ashton Town * | 0-1 | | | | | |
| Sat 28/01/23 | Atherton LR v Ashton Town * | 1-1 | | | | | |
| Sat 04/02/23 | Ashton Town v South Liverpool | 0-0 | | | | | |
| Tue 07/02/23 | Ashton Town v Pilkington | 0-0 | | | | | |
| Sat 11/02/23 | Ashton Town v Euxton Villa | 1-1 | | | | | |
| Sat 18/02/23 | Ashton Town v Holker Old Boys | 0-1 | | | | | |
| Tue 21/02/23 | Ashton Town v Cleator Moor Celtic | 2-0 | | | | | |
| Sat 04/03/23 | Ashton Town v AFC Blackpool | 2-1 | | | | | |
| Sat 18/03/23 | Ashton Town v Daisy Hill | 1-0 | | | | | |
| Sat 25/03/23 | Ashton Town v Runcorn Town | 2-1 | | | | | |
