| Sat 27/07/24 | Maine Road v Steeton | 3-0 | |  | | | | |
| Mon 29/07/24 | Daisy Hill v Maine Road | 1-0 | | | | | | |
| Sat 03/08/24 | Maine Road v Darwen FC | 2-0 | | | | | | |
| Mon 05/08/24 | Maine Road v Bacup Borough | 0-4 | | | | | | |
| Sat 10/08/24 | Garstang v Maine Road * | 0-3 | | | |  | | |
| Tue 13/08/24 | Euxton Villa v Maine Road | 2-1 | | | | | | |
| Sat 17/08/24 | Maine Road v Ashton Town * | 1-2 | | | | | | |
| Mon 19/08/24 | Maine Road v Maghull | 3-2 | | | | | | |
| Sat 24/08/24 | Maine Road v Garstang | 2-0 | | | | | | |
| Mon 26/08/24 | Route One Rovers v Maine Road | 1-1 | | | | | | |
| Sat 31/08/24 | Maine Road v Nelson | 1-3 | | | | | | |
| Sat 07/09/24 | Skelmersdale United v Maine Road * | 0-6 | | | | | | |
| Sat 21/09/24 | Maine Road v Winsford United (CUP) | 1-3 | | | | | | |
| Sat 28/09/24 | Holker Old Boys v Maine Road | 3-2 | | | | | | |
| Mon 30/09/24 | Stockport Town v Maine Road (CUP) * | 5-4 | | | | | | |
| Sat 05/10/24 | Thornton Cleveleys v Maine Road | 0-4 | | | | | | |
| Mon 07/10/24 | Maine Road v Bacup Borough (CUP) | 3-1 | | | | | | |
| Sat 12/10/24 | Maine Road v Euxton Villa | 2-0 | | | | | | |
| Sat 19/10/24 | Ashton Athletic v Maine Road | 1-2 | | |  | | | |
| Sat 26/10/24 | Maine Road v Route One Rovers | 3-1 | | | | | | |
| Sat 02/11/24 | AFC Blackpool v Maine Road | 1-0 | | | | | | |
| Sat 16/11/24 | Maine Road v Ashton Town (CUP) | 3-1 | | | | | | |
| Sat 30/11/24 | Maine Road v Skelmersdale United | 1-2 | | | | | | |
| Thu 26/12/24 | Droylsden v Maine Road | 2-1 | | | | | | |
| Sat 28/12/24 | Maine Road v Thornton Cleveleys * | 4-0 | | | | | | |
| Sat 25/01/25 | Maine Road v Atherton LR * | 1-3 | | | | | | |
| Sat 01/02/25 | Stafford Town v Maine Road (CUP) | 7-4 | | | | | | |
| Sat 08/02/25 | Maghull v Maine Road | 2-1 | | | | | | |
| Sat 15/02/25 | Maine Road v Daisy Hill | 1-1 | | | | | | |
| Sat 01/03/25 | Maine Road v Ashton Athletic | 2-1 | | | | | | |
| Mon 17/03/25 | Maine Road v Holker Old Boys | 0-0 | | | | | | |
| Sat 22/03/25 | Steeton v Maine Road * | 3-4 | | | | | | |
