| Wed 10/08/22 | Albion Sports v Barnoldswick Town * | 2-2 | | | | | |
| Tue 16/08/22 | Barnoldswick Town v Avro | 0-3 | | | | | |
| Sun 21/08/22 | Burscough v Barnoldswick Town | 2-3 |  | | | | |
| Tue 23/08/22 | Barnoldswick Town v Charnock Richard | 2-2 | | | | | |
| Sat 27/08/22 | Blyth Town v Barnoldswick Town | 0-1 | | |  | | |
| Mon 29/08/22 | Barnoldswick Town v Prestwich Heys * | 3-5 | | | | | |
| Sat 03/09/22 | FC Isle of Man v Barnoldswick Town | 3-3 | | | | | |
| Tue 06/09/22 | Barnoldswick Town v Irlam | 3-3 | | | | | |
| Sat 24/09/22 | AFC Blackpool v Barnoldswick Town | 0-3 | | | | | |
| Tue 27/09/22 | Longridge Town v Barnoldswick Town | 2-2 | | | | | |
| Sat 01/10/22 | Barnoldswick Town v Ashton Athletic | 1-2 | | | | | |
| Tue 04/10/22 | Selby Town v Barnoldswick Town | 2-4 | | | | | |
| Fri 07/10/22 | AFC Liverpool v Barnoldswick Town | 3-0 | | | | | |
| Sat 15/10/22 | Barnoldswick Town v Stockport Town | 2-1 | | | | | |
| Sat 22/10/22 | Barnoldswick Town v Selby Town | 5-4 | | | | | |
| Sat 29/10/22 | Lower Breck v Barnoldswick Town | 1-0 | | | | | |
| Tue 08/11/22 | Barnoldswick Town v West Didsbury & Chorlton | 2-1 | | | | |  |
| Sat 12/11/22 | Barnoldswick Town v Horden Community Welfare | 1-2 | | | | | |
| Tue 15/11/22 | Wythenshawe Town v Barnoldswick Town | 2-3 | | | | | |
| Sat 19/11/22 | Barnoldswick Town v Abbey Hey | 1-1 | | | | | |
| Sat 26/11/22 | Barnoldswick Town v Wakefield AFC | 8-3 | | | | | |
| Wed 30/11/22 | Kendal Town v Barnoldswick Town * | 3-1 | | | | | |
| Sat 03/12/22 | Barnoldswick Town v FC Isle of Man | 0-1 | | | | | |
| Tue 06/12/22 | Bury AFC v Barnoldswick Town | 2-0 | | | | | |
| Wed 21/12/22 | Barnoldswick Town v Wythenshawe Town | 3-2 | | | | | |
| Mon 26/12/22 | Padiham v Barnoldswick Town | 1-2 | | | | | |
| Mon 02/01/23 | Barnoldswick Town v AFC Liverpool | 2-1 | | | | | |
| Tue 24/01/23 | Barnoldswick Town v Golcar United | 3-1 | | | | | |
| Thu 26/01/23 | Barnoldswick Town v Northwich Victoria | 3-4 | | | | | |
| Sat 28/01/23 | Barnoldswick Town v Lower Breck | 3-3 | | | | | |
| Tue 31/01/23 | Irlam v Barnoldswick Town | 0-0 | | | | | |
| Wed 08/02/23 | Litherland REMYCA v Barnoldswick Town * | 2-1 | | | | | |
| Sat 11/02/23 | Vauxhall Motors v Barnoldswick Town | 2-0 | | | | | |
| Wed 15/02/23 | Barnoldswick Town v Squires Gate | 0-2 | | | | | |
| Sat 25/02/23 | Northwich Victoria v Barnoldswick Town | 2-0 | | | | | |
| Tue 28/02/23 | Barnoldswick Town v Northwich Victoria | 0-1 | | | | | |
| Sat 04/03/23 | Barnoldswick Town v Burscough | 1-1 | | | | | |
| Wed 12/04/23 | Barnoldswick Town v Longridge Town * | 2-4 | | | | | |
