| Wed 07/08/24 | Pilkington v Wythenshawe (CUP) | 3-1 | | | | | | |
| Mon 26/08/24 | Pilkington v Colne | 1-1 | | | | | | |
| Sat 31/08/24 | Irlam v Pilkington | 3-1 | | | | | | |
| Wed 04/09/24 | Pilkington v Longridge Town | 3-6 | | | | | | |
| Tue 24/09/24 | Burscough v Pilkington * | 3-2 | | | | | | |
| Sat 12/10/24 | Colne v Pilkington | 2-4 |  | | | | | |
| Sat 19/10/24 | Pilkington v Prestwich Heys | - | |  | | | | |
| Sat 26/10/24 | Pilkington v AFC Liverpool | 1-2 | | | | | | |
| Sat 02/11/24 | Bury v Pilkington | 2-0 | | | | | |  |
| Sat 09/11/24 | Pilkington v Prestwich Heys | 3-2 | | | | | | |
| Sat 16/11/24 | Ramsbottom United v Pilkington | 2-0 | | | | | | |
| Sat 23/11/24 | Pilkington v FC Isle of Man | 3-3 | | | |  | | |
| Wed 27/11/24 | Pilkington v South Liverpool | 4-3 | | | | | | |
| Sat 14/12/24 | Pilkington v Glossop North End | 1-3 | | | | | | |
| Sat 21/12/24 | Cheadle Town v Pilkington * | 4-0 | | | | | | |
| Thu 26/12/24 | FC St Helens v Pilkington | 2-1 | | | | | | |
| Thu 23/01/25 | Lower Breck v Pilkington | 5-0 | | | | | | |
| Sat 01/02/25 | AFC Liverpool v Pilkington | 2-0 | | |  | | | |
| Sat 08/02/25 | Pilkington v FC St Helens * | 0-1 | | | | | | |
| Sat 15/02/25 | Prestwich Heys v Pilkington | 2-2 | | | | | | |
| Sat 22/02/25 | West Didsbury & Chorlton v Pilkington * | 3-1 | | | | | | |
| Sat 01/03/25 | Pilkington v Barnoldswick Town * | 2-0 | | | | | | |
| Sat 08/03/25 | Stockport Town v Pilkington | 2-1 | | | | | | |
| Sat 15/03/25 | FC Isle of Man v Pilkington | 3-3 | | | | | | |
| Sat 22/03/25 | Pilkington v Bury | 0-2 | | | | | | |
| Sat 29/03/25 | Longridge Town v Pilkington | 0-2 | | | | | | |
| Fri 04/04/25 | Chadderton v Pilkington | 4-1 | | | | | | |
| Sat 12/04/25 | Pilkington v Squires Gate | 3-1 | | | | | | |
| Sat 19/04/25 | Glossop North End v Pilkington | 4-0 | | | | | | |
