| Sat 03/09/22 | Ashton Town v Ilkley Town * | 1-4 | | | | | |
| Tue 27/09/22 | AFC Blackpool v Ashton Town | 0-0 | | | | | |
| Sat 01/10/22 | Holker Old Boys v Ashton Town | 6-2 | | | | | |
| Sat 08/10/22 | Ashton Town v Runcorn Town | 2-0 | | | | | |
| Sat 15/10/22 | Garstang v Ashton Town | 2-1 | | | | | |
| Sat 22/10/22 | Ashton Town v Chadderton | 0-3 | | | | | |
| Wed 26/10/22 | Pilkington v Ashton Town | 4-3 | | | | | |
| Sat 29/10/22 | FC St Helens v Ashton Town | 6-0 | | | | | |
| Sat 05/11/22 | Ashton Town v Darwen FC | 5-3 | | | | | |
| Sat 12/11/22 | Ashton Town v Steeton | 1-3 | | | | | |
| Sat 19/11/22 | Ilkley Town v Ashton Town | 1-2 | | | | |  |
| Tue 22/11/22 | Euxton Villa v Ashton Town | 2-0 | | | | | |
| Fri 02/12/22 | South Liverpool v Ashton Town * | 2-1 | | | | | |
| Tue 27/12/22 | Ashton Town v Garstang | 1-0 | | | | | |
| Sat 14/01/23 | Darwen FC v Ashton Town | 7-0 | | | | | |
| Sat 28/01/23 | Atherton LR v Ashton Town * | 1-1 | | | | | |
| Sat 04/02/23 | Ashton Town v South Liverpool | 0-0 | | | | | |
| Tue 07/02/23 | Ashton Town v Pilkington | 0-0 | | | | | |
| Sat 11/02/23 | Ashton Town v Euxton Villa | 1-1 | | | | | |
| Sat 18/02/23 | Ashton Town v Holker Old Boys | 0-1 | | | | | |
| Tue 21/02/23 | Ashton Town v Cleator Moor Celtic | 2-0 | | | | | |
| Tue 28/02/23 | Chadderton v Ashton Town | 2-0 | | | | | |
| Sat 04/03/23 | Ashton Town v AFC Blackpool | 2-1 |  | | | | |
| Sat 18/03/23 | Ashton Town v Daisy Hill | 1-0 | | | | | |
| Sat 25/03/23 | Ashton Town v Runcorn Town | 2-1 | | | | | |
| Sat 01/04/23 | Cleator Moor Celtic v Ashton Town | 2-2 | | | | | |
| Sat 08/04/23 | Nelson v Ashton Town | 2-0 | | | | | |
| Thu 13/04/23 | Garstang v Ashton Town | 0-2 | | |  | | |
| Sat 15/04/23 | Ashton Town v FC St Helens | 1-1 | | | | | |
| Fri 21/04/23 | Bacup Borough v Ashton Town | 4-1 | | | | | |
