| Sat 26/07/25 | Runcorn Town v Market Drayton Town | 4-0 | | | | | | |
| Tue 29/07/25 | Shawbury United v Market Drayton Town | 3-2 |  | | | | |  |
| Sat 02/08/25 | Market Drayton Town v Stockport Georgians | 3-1 | | | | | | |
| Sat 09/08/25 | Foley Meir v Market Drayton Town | 2-0 | | | | | | |
| Sat 23/08/25 | Market Drayton Town v Haughmond (CUP) | 1-3 | | | |  | | |
| Sat 06/09/25 | Cheadle Heath Nomads v Market Drayton Town | 2-3 | | | | | | |
| Tue 09/09/25 | Market Drayton Town v Wolverhampton Casuals | 2-2 | | | | | | |
| Sat 13/09/25 | Market Drayton Town v Allscott Heath | 1-3 | | | | | | |
| Tue 16/09/25 | Sandbach United v Market Drayton Town | 2-1 | | | | | | |
| Fri 19/09/25 | Market Drayton Town v Shawbury United | 3-3 | | | | | | |
| Sat 27/09/25 | Eccleshall v Market Drayton Town (CUP) | 3-1 | | | | | | |
| Sat 04/10/25 | Market Drayton Town v Stafford Town | 3-3 | | | | | | |
| Tue 07/10/25 | Shawbury United v Market Drayton Town (CUP) | 3-3 | | | | | | |
| Sat 11/10/25 | Market Drayton Town v Alsager Town | 1-4 | | | | | | |
| Sat 18/10/25 | Telford Town v Market Drayton Town | 1-0 | | | | | | |
| Tue 21/10/25 | Market Drayton Town v Haughmond | 5-2 | | | | | | |
| Sat 25/10/25 | Stockport Georgians v Market Drayton Town | 1-1 | | | | | | |
| Sat 01/11/25 | New Mills v Market Drayton Town | 3-1 | | | | | | |
| Sat 08/11/25 | Market Drayton Town v Cheadle Heath Nomads | 0-0 | |  | | | | |
| Sat 15/11/25 | Allscott Heath v Market Drayton Town | 2-2 | | | | | | |
| Sat 22/11/25 | Wolverhampton Sporting Community v Market Drayton Town | 1-3 | | | | | | |
| Sat 13/12/25 | Wolverhampton Casuals v Market Drayton Town | 0-0 | | | | | | |
| Fri 26/12/25 | Eccleshall v Market Drayton Town | 2-0 | | | | | | |
| Sat 03/01/26 | Market Drayton Town v Sandbach United | - | | | | | | |
| Sat 10/01/26 | Cammell Laird 1907 v Market Drayton Town | 2-0 | | | | | | |
| Sat 17/01/26 | Market Drayton Town v Runcorn Town * | 0-7 | | | | | | |
