| Tue 03/08/21 | Bacup Borough v Ilkley Town * | 3-0 | | | | | |
| Sat 04/09/21 | Bacup Borough v AFC Darwen * | 3-0 | | |  | | |
| Tue 07/09/21 | Campion v Bacup Borough | 0-2 | | | | | |
| Sat 11/09/21 | Bacup Borough v Penistone Church | 1-0 | | | | | |
| Sat 18/09/21 | Daisy Hill v Bacup Borough | 1-1 | | | | | |
| Sat 02/10/21 | St Helens Town v Bacup Borough | 1-2 | | | | | |
| Sat 30/10/21 | Nelson v Bacup Borough | 0-4 | | | | | |
| Sat 06/11/21 | Bacup Borough v Atherton LR | 6-0 | | | | | |
| Tue 09/11/21 | Bacup Borough v South Liverpool | 1-1 | | | | | |
| Sat 20/11/21 | Bacup Borough v Nelson | 3-2 | | | | | |
| Sat 11/12/21 | Bacup Borough v Garstang | - | | | | | |
| Sat 18/12/21 | Ilkley Town v Bacup Borough | 1-1 | | | | | |
| Sat 15/01/22 | Ashton Town v Bacup Borough * | 3-0 | | | | | |
| Tue 18/01/22 | Bacup Borough v Garstang | 4-1 | | | | | |
| Sat 22/01/22 | Bacup Borough v Campion | 3-1 | | | | | |
| Sat 29/01/22 | Bacup Borough v Golcar United | 1-1 | | | |  | |
| Sat 05/03/22 | Bacup Borough v St Helens Town | 6-1 | | | | | |
| Sat 12/03/22 | AFC Blackpool v Bacup Borough | 5-3 | | | | | |
| Sat 19/03/22 | Bacup Borough v Bury AFC | 1-2 | | | | |  |
| Tue 22/03/22 | Chadderton v Bacup Borough | 0-0 | | | | | |
| Sat 26/03/22 | Atherton LR v Bacup Borough | 2-1 | | | | | |
| Tue 29/03/22 | Bacup Borough v Holker Old Boys | 1-0 | | | | | |
| Thu 31/03/22 | Bacup Borough v Daisy Hill | 1-2 | | | | | |
| Sat 02/04/22 | Steeton v Bacup Borough | 4-2 | | | | | |
| Sat 09/04/22 | Bacup Borough v Ilkley Town | 3-3 | | | | | |
| Wed 20/04/22 | Avro v Bacup Borough | 2-3 | | | | | |
| Sat 30/04/22 | Congleton Town v Bacup Borough | 1-0 | | | | | |
