| Sat 03/08/24 | Holker Old Boys v Droylsden * | 4-0 | | | | | | |
| Tue 06/08/24 | Droylsden v Ashton Town * | 3-1 | | | | | | |
| Sat 10/08/24 | Droylsden v Steeton | 6-1 | | | | | | |
| Wed 14/08/24 | Nelson v Droylsden * | 1-2 | | | | | | |
| Sat 17/08/24 | AFC Blackpool v Droylsden * | 3-5 | | | | | | |
| Tue 20/08/24 | Droylsden v Ashton Athletic * | 5-1 | | | | | | |
| Sat 24/08/24 | Burscough v Droylsden (CUP) * | 2-1 | | | | | | |
| Mon 26/08/24 | Daisy Hill v Droylsden * | 1-1 | | | | | | |
| Sat 31/08/24 | Droylsden v Skelmersdale United * | 3-0 | |  | | | | |
| Sat 14/09/24 | Droylsden v Route One Rovers * | 0-0 | | | | | | |
| Sat 21/09/24 | Skelmersdale United v Droylsden * | 1-2 | | | | | | |
| Tue 01/10/24 | Droylsden v Abbey Hey (CUP) * | 4-0 |  | | | | | |
| Sat 05/10/24 | Maghull v Droylsden * | 2-0 | | | | | | |
| Tue 08/10/24 | Droylsden v AFC Blackpool (CUP) | - | | | | | | |
| Sat 12/10/24 | Droylsden v Thornton Cleveleys | 7-0 | | | | | | |
| Tue 15/10/24 | Droylsden v AFC Blackpool (CUP) | 4-1 | | | | | | |
| Sat 26/10/24 | Droylsden v Nelson | 1-0 | | | | | | |
| Sat 02/11/24 | Steeton v Droylsden | 0-3 | | | | | | |
| Sat 09/11/24 | Droylsden v Euxton Villa (CUP) * | 2-3 | | | | | | |
| Sat 16/11/24 | Droylsden v Maghull | 1-0 | | | |  | | |
| Mon 18/11/24 | Stockport Town v Droylsden (CUP) | 0-3 | | | | | | |
| Sat 30/11/24 | Droylsden v AFC Blackpool | 1-0 | | | | | | |
| Thu 26/12/24 | Droylsden v Maine Road * | 2-1 | | | | | | |
| Sat 28/12/24 | Garstang v Droylsden | 1-3 | | | | | | |
| Sat 25/01/25 | Euxton Villa v Droylsden | 1-2 | | | | | | |
| Sat 01/02/25 | Darwen FC v Droylsden | 0-1 | | | | | | |
| Sat 08/02/25 | Ashton Town v Droylsden | 2-2 | | | | | | |
| Sat 15/02/25 | Route One Rovers v Droylsden | 1-3 | | | | | | |
| Sat 22/02/25 | Bacup Borough v Droylsden * | 2-0 | | | | | | |
| Sun 02/03/25 | Droylsden v Darwen FC | 3-2 | | | | | | |
| Sat 08/03/25 | Droylsden v Daisy Hill | 1-2 | | | | | | |
| Sat 22/03/25 | Ashton Athletic v Droylsden | 0-4 | | | | | | |
