| Sat 26/07/25 | South Liverpool v Stockport Town * | 0-3 | | | | | | |
| Sat 02/08/25 | Bury v South Liverpool (CUP) * | 6-0 | | | | | | |
| Sat 16/08/25 | Pilkington v South Liverpool * | 1-6 | | | | | | |
| Mon 25/08/25 | South Liverpool v Burscough * | 0-3 | | | | | | |
| Sat 30/08/25 | Glossop North End v South Liverpool * | 0-1 | |  | | | | |
| Wed 17/09/25 | South Liverpool v Abbey Hey * | 5-3 | | | | | | |
| Sat 08/11/25 | South Liverpool v Barton Town (CUP) * | 4-0 | | | | | | |
| Sat 22/11/25 | South Liverpool v Irlam * | 0-3 | | | | | | |
| Tue 02/12/25 | FC St Helens v South Liverpool * | 3-1 | | | | | | |
| Sat 06/12/25 | Albion Sports v South Liverpool (CUP) * | 0-3 | | | | | | |
| Wed 10/12/25 | Litherland REMYCA v South Liverpool (CUP) | 1-4 | | | | | | |
| Sat 13/12/25 | Barnoldswick Town v South Liverpool | 0-0 | | | | | | |
| Wed 17/12/25 | South Liverpool v Cheadle Town | 2-2 | | | | | | |
| Sat 20/12/25 | South Liverpool v Padiham | 1-0 | | | | | | |
| Sat 03/01/26 | South Liverpool v Wythenshawe * | 1-3 | | | | | | |
| Sat 17/01/26 | South Liverpool v Winsford United (CUP) * | 2-5 | | | | | | |
| Wed 28/01/26 | South Liverpool v Pilkington * | 3-1 | | | | | | |
| Wed 04/02/26 | South Liverpool v Ramsbottom United * | 0-2 | | | | | | |
| Wed 25/02/26 | South Liverpool v Warrington Rylands 1906 (CUP) * | 0-3 | | | | | | |
| Sat 28/02/26 | Stockport Town v South Liverpool * | 1-1 | | | | | | |
| Tue 03/03/26 | Irlam v South Liverpool | 0-2 | | | | | | |
| Sat 07/03/26 | Padiham v South Liverpool | 1-0 | | | | | | |
| Sat 14/03/26 | South Liverpool v AFC Liverpool | 1-1 | | | | | | |
| Sat 11/04/26 | Ramsbottom United v South Liverpool * | 2-0 | | | | | | |
| Sat 18/04/26 | South Liverpool v Glossop North End | 0-2 | | | | | |  |
