| Sat 05/10/24 | West Didsbury & Chorlton v Barnoldswick Town * | 2-1 | | | | | | |
| Tue 08/10/24 | Abbey Hey v West Didsbury & Chorlton * | 1-3 | | | | | | |
| Sat 12/10/24 | West Didsbury & Chorlton v Charnock Richard * | 2-1 | | | | | | |
| Tue 15/10/24 | West Didsbury & Chorlton v Lower Breck | 3-0 | |  | | | | |
| Sat 19/10/24 | West Didsbury & Chorlton v Stockport Town (CUP) | 2-0 | | | | | | |
| Tue 22/10/24 | Barnoldswick Town v West Didsbury & Chorlton * | 1-0 | | | | | | |
| Sat 26/10/24 | West Didsbury & Chorlton v FC St Helens | 3-1 | | | | | | |
| Tue 29/10/24 | Prestwich Heys v West Didsbury & Chorlton | 2-2 | | | | | | |
| Sat 09/11/24 | Ryton & Crawcrook Albion v West Didsbury & Chorlton (CUP) * | 0-2 |  | | | | | |
| Tue 12/11/24 | Irlam v West Didsbury & Chorlton * | 3-2 | | | | | | |
| Sat 14/12/24 | West Didsbury & Chorlton v Silsden (CUP) * | 5-1 | | | | | | |
| Sat 21/12/24 | South Liverpool v West Didsbury & Chorlton * | 0-2 | | | | | | |
| Thu 26/12/24 | West Didsbury & Chorlton v Cheadle Town * | 1-0 | | | | | | |
| Sat 28/12/24 | Chadderton v West Didsbury & Chorlton | 1-6 | | | | | | |
| Sat 04/01/25 | West Didsbury & Chorlton v Bury * | 4-0 | | | | | | |
| Wed 08/01/25 | Chadderton v West Didsbury & Chorlton (CUP) | 2-2 | | | | | | |
| Tue 21/01/25 | West Didsbury & Chorlton v Squires Gate | 4-1 | | | | | | |
| Sat 01/02/25 | West Didsbury & Chorlton v Colne * | 4-3 | | | | | | |
| Tue 04/02/25 | West Didsbury & Chorlton v Prestwich Heys * | 1-2 | | | | | | |
| Sat 08/02/25 | Charnock Richard v West Didsbury & Chorlton * | 2-5 | | | | | | |
| Sat 15/02/25 | Bury v West Didsbury & Chorlton * | 2-1 | | | | | | |
| Sat 22/02/25 | West Didsbury & Chorlton v Pilkington * | 3-1 | | | | | | |
| Wed 26/02/25 | Litherland REMYCA v West Didsbury & Chorlton * | 1-1 | | | | | | |
| Sat 01/03/25 | Glossop North End v West Didsbury & Chorlton * | 0-2 | | | | | | |
| Thu 06/03/25 | Lower Breck v West Didsbury & Chorlton | 3-1 | | | | | | |
| Sat 08/03/25 | Cheadle Town v West Didsbury & Chorlton * | 3-4 | | | | | | |
| Sat 15/03/25 | West Didsbury & Chorlton v Padiham * | 1-1 | | | | | | |
| Sat 22/03/25 | Ramsbottom United v West Didsbury & Chorlton * | 1-0 | | | | | | |
