| Sat 27/07/24 | Skelmersdale United v Atherton LR | 1-2 | | | | | | |
| Wed 31/07/24 | Darwen FC v Skelmersdale United | 5-2 | | | | | | |
| Sat 03/08/24 | Skelmersdale United v Ashton Athletic | 0-1 | | | | | | |
| Tue 06/08/24 | Skelmersdale United v Maghull | 0-5 | | | | | | |
| Tue 03/09/24 | Skelmersdale United v Euxton Villa | 2-4 | | | | | | |
| Sat 07/09/24 | Skelmersdale United v Maine Road | 0-6 | | | |  | | |
| Sat 21/09/24 | Skelmersdale United v Droylsden | 1-2 | | | | | | |
| Sat 28/09/24 | Thornton Cleveleys v Skelmersdale United | 1-0 | | | | | | |
| Sat 05/10/24 | Skelmersdale United v Holker Old Boys | 0-9 | | | | | | |
| Tue 08/10/24 | Skelmersdale United v Maghull (CUP) | 0-2 | | | | | | |
| Sat 12/10/24 | Ashton Athletic v Skelmersdale United | 2-0 | | | | | |  |
| Mon 14/10/24 | Daisy Hill v Skelmersdale United (CUP) | 1-0 | | | | | | |
| Sat 19/10/24 | Skelmersdale United v AFC Blackpool | 1-4 | | | | | | |
| Sat 26/10/24 | Bacup Borough v Skelmersdale United | 2-1 | | | | | | |
| Tue 29/10/24 | Warrington Rylands 1906 v Skelmersdale United (CUP) | 10-1 | | | | | | |
| Sat 02/11/24 | Skelmersdale United v Darwen FC | 1-6 | | | | | | |
| Sat 16/11/24 | Skelmersdale United v Nelson | 0-5 | | | | | | |
| Sat 30/11/24 | Maine Road v Skelmersdale United | 1-2 | | | | | | |
| Sat 14/12/24 | Holker Old Boys v Skelmersdale United | 4-0 | | | | | | |
| Sat 28/12/24 | Skelmersdale United v Ashton Town | 0-3 | | | | | | |
| Sat 04/01/25 | Steeton v Skelmersdale United | 3-1 | | | | | | |
| Sat 25/01/25 | Route One Rovers v Skelmersdale United | 2-0 | | | | | | |
| Sat 15/02/25 | Skelmersdale United v Garstang | 2-1 | | | | | | |
| Fri 28/02/25 | Euxton Villa v Skelmersdale United | 4-0 | | | | | | |
| Sat 22/03/25 | Atherton LR v Skelmersdale United | 3-0 | | | | | | |
| Sat 29/03/25 | Skelmersdale United v Thornton Cleveleys | 0-3 | | | | | | |
| Tue 01/04/25 | Skelmersdale United v Daisy Hill | 0-5 | | | | | | |
| Sat 05/04/25 | Ashton Town v Skelmersdale United | 5-0 | | | | | | |
| Sat 12/04/25 | Skelmersdale United v Bacup Borough | 1-3 | | | | | | |
