There were 3 registrations between 1/4/2022 and 8/4/2022. There were also 10 deregistrations. These have been coordinated by the NWCFL League Registrations Secretary, Rob Goodwin-Davey.
| Club | Player Name | Date Registered | Reg Type | Role |
| Abbey Hey | Jake Parker | Wednesday 6th April 2022 | Short Loan | |
| Brocton | Christopher Curtis | Friday 8th April 2022 | Staff | Coach |
| Stafford Town | Ryan Cheshire | Saturday 2nd April 2022 | Temporary |
| Club | Player Name | Date De-Registered | Reg Type | Role |
| Abbey Hey | Jake Parker | Tuesday 5th April 2022 | Short Loan | |
| AFC Liverpool | Max Fisher | Tuesday 5th April 2022 | Work Experience | |
| Charnock Richard | Harry Scarborough | Monday 4th April 2022 | Short Loan | |
| Litherland REMYCA | Oscar Billington | Friday 1st April 2022 | Non Contract | |
| Lower Breck | Warren Gerrard | Sunday 3rd April 2022 | Short Loan | |
| Lower Breck | Ellis Litherland-Riding | Tuesday 5th April 2022 | Work Experience | |
| Macclesfield | Brandon Lonsdale | Saturday 2nd April 2022 | Work Experience | |
| Stockport Town | Lucas Berry | Tuesday 5th April 2022 | Work Experience | |
| Stockport Town | Ben Finley | Tuesday 5th April 2022 | Work Experience | |
| Vauxhall Motors | Michael Dixon | Friday 1st April 2022 | Non Contract |
