| Monday 5th October 2026 | The Edward Case Cup 1st Round North | ||
| 19:45 |  Maine Road v Holker Old Boys  | Brantingham Road | |
| Monday 5th October 2026 | The Edward Case Cup 1st Round South | ||
| 19:45 |  Cheadle Heath Nomads v Wolverhampton Casuals  | Ideal Building Systems Stadium | |
| Tuesday 6th October 2026 | The Edward Case Cup 1st Round North | ||
| 19:45 |  Flixton v Darwen FC  | Valley Road | |
| 19:45 |  Fulwood Amateurs v Ashton Town  | Lightfoot Green Lane | |
| 19:45 |  Maghull v Cammell Laird 1907  | DT Hughes Community Stadium | |
| 19:45 |  Squires Gate v Steeton  | The Skiddle Community Stadium | |
| 19:45 |  Uppermill v Thornton Cleveleys  | Seel Park | |
| Tuesday 6th October 2026 | The Edward Case Cup 1st Round South | ||
| 19:45 |  Market Drayton Town v Alsager Town  | Balufab Stadium | |
| 19:45 |  Sandbach United v Foley Meir  | Sandbach Community Football Centre | |
| 19:45 |  Telford Town v Shawbury United  | Lionheart Security Services Stadium | |
| 19:45 |  Wednesfield Community v New Mills  | Cottage Ground | |
| 20:00 |  Stafford Town v Allscott Heath  | Evans Park | |
| Wednesday 7th October 2026 | The Edward Case Cup 1st Round North | ||
| 19:45 |  Woolton v Colne  | Simpsons Sports Ground (4G) | |
| 20:00 |  Bacup Borough v Ashville  | Brian Boys West View Stadium | |
| Wednesday 7th October 2026 | The Edward Case Cup 1st Round South | ||
| 19:45 |  Barnton v Eccleshall  | The Creative Hut Stadium | |
| 19:45 |  Brereton Social v AFC Bridgnorth  | Red Lion Ground | |
| Monday 5th October 2026 The Edward Case Cup 1st Round North |
| Maine Road v Holker Old Boys (19:45) |
| Monday 5th October 2026 The Edward Case Cup 1st Round South |
| Cheadle Heath Nomads v Wolverhampton Casuals (19:45) |
| Tuesday 6th October 2026 The Edward Case Cup 1st Round North |
| Flixton v Darwen FC (19:45) |
| Fulwood Amateurs v Ashton Town (19:45) |
| Maghull v Cammell Laird 1907 (19:45) |
| Squires Gate v Steeton (19:45) |
| Uppermill v Thornton Cleveleys (19:45) |
| Tuesday 6th October 2026 The Edward Case Cup 1st Round South |
| Market Drayton Town v Alsager Town (19:45) |
| Sandbach United v Foley Meir (19:45) |
| Telford Town v Shawbury United (19:45) |
| Wednesfield Community v New Mills (19:45) |
| Stafford Town v Allscott Heath (20:00) |
| Wednesday 7th October 2026 The Edward Case Cup 1st Round North |
| Woolton v Colne (19:45) |
| Bacup Borough v Ashville (20:00) |
| Wednesday 7th October 2026 The Edward Case Cup 1st Round South |
| Barnton v Eccleshall (19:45) |
| Brereton Social v AFC Bridgnorth (19:45) |
